trans-4-(Trifluoromethyl)cyclohexanol(CAS: 75091-93-9)

Trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9) is a colorless, slightly viscous liquid with a high boiling point of 230°C. It has a molecular weight of approximately 171.12 g/mol and is only slightly soluble in water. The compound is relatively stable but can react with strong bases. It has a high dielectric constant, making it useful in various chemical applications.

Trans-4-(Trifluoromethyl)cyclohexanol is typically synthesized via an olefin metathesis reaction of trans-4-(trifluoromethyl)cyclohexene with water, followed by reduction of the resulting aldehyde. This process uses ruthenium-based catalysts and results in a yield of about 90%. The reaction is selective and provides a high level of purity.

Trans-4-(Trifluoromethyl)cyclohexanol is primarily used in the pharmaceutical and polymer industries. It serves as a precursor for the synthesis of medicinals and as a building block for advanced polymers with unique properties. Its use in sensors and semiconductors is also expanding due to its electrical and chemical stability.

When handling trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9), it is important to wear appropriate personal protective equipment (PPE) including safety goggles, gloves, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to prevent inhalation. Spills should be handled using appropriate absorbents and cleaned up according to standard laboratory procedures. Refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.