7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1) | CAS No. 75001-77-3
7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1)
Basic Information
CAS Number
75001-77-3
Molecular Formula
C14H17ClFN3O3
Molecular Weight
329.76 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Desethylene Norfloxacin Hydrochloride
- Norfloxacin impurity B
- Norfloxacin Impurity B(EP)
- 7-((2-aminoethyl)amino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
FAQ
What are the physical and chemical properties of 7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 75001-77-3)?
The compound has a crystalline form with a molecular weight of approximately 317.7 g/mol. It is slightly soluble in water and more soluble in organic solvents. It is known for its acidic nature, with a pKa value around 2.6. The compound is reactive towards basic conditions and can undergo hydrolysis. It is important to use appropriate protective measures when handling this compound to avoid irritation or other adverse effects.
How is 7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 75001-77-3) typically synthesized?
This compound is typically synthesized through a multi-step process involving the reaction of 2-aminoethylamine with 1-ethyl-6-fluoro-3-quinolinecarboxylic acid. The key steps include the formation of the amide bond and the subsequent protonation to form the hydrochloride salt. The reaction is catalyzed by appropriate bases and is carried out under controlled conditions to achieve high yield and selectivity.
What industries use 7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 75001-77-3)?
This compound is primarily used in the pharmaceutical industry for the production of certain drugs due to its biological activity. It is also utilized in the semiconductor industry for its properties related to conductivity and stability. Additionally, it has applications in sensor technology and as a precursor in organic synthesis.
What precautions should be taken when handling 7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 75001-77-3)?
When handling this compound, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a fume hood to minimize exposure to air and moisture. In case of a spill, the area should be immediately flushed with water and cleaned up using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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