Compound Q&A

How is 7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 75001-77-3) typically synthesized?

Answer

7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1)
This compound is typically synthesized through a multi-step process involving the reaction of 2-aminoethylamine with 1-ethyl-6-fluoro-3-quinolinecarboxylic acid. The key steps include the formation of the amide bond and the subsequent protonation to form the hydrochloride salt. The reaction is catalyzed by appropriate bases and is carried out under controlled conditions to achieve high yield and selectivity.

About

CAS No 75001-77-3
English Name 7-[(2-Aminoethyl)amino]-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1)
Molecular Formula C14H17ClFN3O3
Molecular Weight 329.76 g/mol
SMILES CCn1cc(c(=O)c2c1cc(c(c2)F)NCCN)C(=O)O.Cl
InChIKey XUUCXAJCEZVOEZ-UHFFFAOYSA-N
Last Updated: 2026-03-08 09:14

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