2-Propanamine

Basic Information

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CAS Number

75-31-0

Molecular Formula

C3H9N

Molecular Weight

59.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

-95°C

Boiling Point

33-34 °C

Density

0.688 g/mL at 20 °C

Solubility

1000g/l

Refractive Index

n20/D 1.374(lit.)

Vapor Pressure

9.2 psi ( 20 °C)

SMILES

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CC(C)N

InChI

InChI=1S/C3H9N/c1-3(2)4/h3H,4H2,1-2H3

InChIKey

JJWLVOIRVHMVIS-UHFFFAOYSA-N

LogP

0.35350000000000004

pKa

10.63(at 25℃)

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

10.8

Safety Information

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Hazard Statement

H224 Extremely flammable liquid and vapor
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Stability

Stable. Extremely flammable - note low boiling point and low flash point. Readily forms explosive mixtures with air. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, perchloryl fluoride.

Sensitiveness

Air Sensitive

Explosive Limit

2-10.4%(V)

Toxicity

LD50 orally in rats: 820 mg/kg (Smyth)

Synonyms & References

English

Isopropylamine
2-Aminopropane
iso-Propyl-d7-amine
PropyldamineatomD
monoisopropylamine
1-Methylethylamine
2-Propanamine
2-Propylamine
propan-2-amine
Propane,2-amino
sec-Propylamine

MDL Number

MFCD00008082

FAQ

What regulatory guidelines apply to 2-Propanamine (CAS: 75-31-0)?

2-Propanamine (CAS: 75-31-0) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a skin irritant and a toxic substance. It is also subject to the REACH regulations in the European Union, requiring registration for quantities above 1 ton per year. The Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) in the U.S. have specific labeling and handling requirements for this compound, especially in the context of pharmaceuticals and cosmetics.

Are there alternatives to 2-Propanamine (CAS: 75-31-0) in synthesis?

2-Propanamine (CAS: 75-31-0) can be synthesized from other compounds like 2-propanol. However, alternatives such as morpholine and piperidine are sometimes used as they offer similar amine functionality with different reactivity. These alternatives can provide safer working conditions and reduced toxicity in certain applications.

What is the market or research trend for 2-Propanamine (CAS: 75-31-0)?

The market for 2-Propanamine (CAS: 75-31-0) is growing due to its use in pharmaceuticals and personal care products. Research trends are focusing on its application in drug development and as a precursor in synthetic chemistry. There is also increasing interest in developing more sustainable and environmentally friendly synthesis methods to reduce the environmental impact of its production and use.

How should waste containing 2-Propanamine (CAS: 75-31-0) be handled?

Waste containing 2-Propanamine (CAS: 75-31-0) should be collected in a leak-proof container and stored in a well-ventilated area away from sources of ignition. It should be disposed of through a professional hazardous waste disposal service that adheres to local regulations. Proper incineration or chemical treatment is recommended to ensure complete degradation of the compound and to minimize environmental impact.