6-Chloro-1H-pyrrolo[3,2-c]pyridine

Basic Information

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CAS Number

74976-31-1

Molecular Formula

C7H5ClN2

Molecular Weight

152.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

335.8℃ at 760 mmHg

SMILES

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C1=CNC2=CC(=NC=C21)Cl

InChI

InChI=1S/C7H5ClN2/c8-7-3-6-5(4-10-7)1-2-9-6/h1-4,9H

InChIKey

CBHXTZKXDLDMJZ-UHFFFAOYSA-N

LogP

2.2162999999999995

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

129

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-Chloro-5-azaindole
AM20061484
2,4-Dichloro-3-ethyl-6-aminophenolhydrochloride
FT-0650247
ME-0200
MFCD08690133
J-518501
6-chloro-5-aza indole
PB22198
AKOS005259006
A838289
AC-25265
6-Choro-5-azaindole
CBHXTZKXDLDMJZ-UHFFFAOYSA-N
BCP07759
SY040826
CS-W003926
6-chloro-1H-pyrrolo[3,2-c]pyridine;6-Chloro-5-azaindole
6-chloro-5-aza-indole
SCHEMBL1233148
6-Chloro-1H-pyrrolo[3,2-c]pyridine
DTXSID50503112
74976-31-1
1H-Pyrrolo[3,2-c]pyridine, 6-chloro-
6-Chloro-5-azaindol
976C311
PubChem23086
KSC494E0R
HIN1573
WT1446
FCH862473

MDL Number

MFCD08690133

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Chloro-1H-pyrrolo[3,2-c]pyridine (CAS: 74976-31-1)?

6-Chloro-1H-pyrrolo[3,2-c]pyridine is a crystalline solid with a molecular weight of approximately 192.01 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored away from moisture and heat.

How is 6-Chloro-1H-pyrrolo[3,2-c]pyridine (CAS: 74976-31-1) typically synthesized?

6-Chloro-1H-pyrrolo[3,2-c]pyridine can be synthesized via chlorination of 1H-pyrrolo[3,2-c]pyridine. The reaction involves the use of thionyl chloride as a chlorinating agent. The reaction is carried out in an inert atmosphere to avoid side reactions, and the product can be purified by recrystallization or column chromatography.

What industries use 6-Chloro-1H-pyrrolo[3,2-c]pyridine (CAS: 74976-31-1)?

6-Chloro-1H-pyrrolo[3,2-c]pyridine is used in the pharmaceutical industry for the synthesis of certain antipsychotic drugs. It is also used in the semiconductor industry as a dopant for organic semiconductors and in the polymer industry for the development of conductive polymers.

What precautions should be taken when handling 6-Chloro-1H-pyrrolo[3,2-c]pyridine (CAS: 74976-31-1)?

When handling 6-Chloro-1H-pyrrolo[3,2-c]pyridine, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation. Spills should be cleaned up carefully, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.