3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] | CAS No. 747353-15-7
3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine]
Basic Information
CAS Number
747353-15-7
Molecular Formula
C13H17NO
Molecular Weight
203.28 g/mol
AD
Basic Physical Properties
Boiling Point
336℃
Density
1.11
Flash Point
134℃
Synonyms & References
English
- 1-methylspiro[1H-2-benzofuran-3,4'-piperidine]
- (RS)-3-methyl-3H-spiro[2-benzofuran-1,4'-piperidine]
- 3-METHYL-3H-SPIRO[ISOBENZOFURAN-1,4'-PIPERIDINE]
- SureCN736557
- 3-methyl-1'H,3H-spiro[2-benzofuran-1,4'-piperidine]
- 3-methyl-3H-spiro[[2]benzofuran-1,4'-piperidine]
- Spiro[isobenzofuran-1(3H),4'-piperidine], 3-methyl-
- 3-methyl-3H-spiro[2-benzofuran-1,4'-piperidine]
Customs Code
2934999090
FAQ
What are the physical and chemical properties of 3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 747353-15-7)?
3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] is a solid with a crystalline form. Its molecular weight is approximately 250.32 g/mol. This compound is poorly soluble in water but soluble in organic solvents like dichloromethane and ethanol. It is moderately reactive, particularly towards nucleophiles and electrophiles. It has a pKa of around 8.0, indicating basicity.
How is 3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 747353-15-7) typically synthesized?
3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] is typically synthesized via the reaction of benzofuran and piperidine under basic conditions using sodium hydride as a catalyst. The yield is generally around 70-80%, and the reaction involves the formation of a spiro cyclohexane intermediate. The product is purified by recrystallization from a suitable solvent.
What industries use 3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 747353-15-7)?
3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] is primarily used in the pharmaceutical industry for the development of new drugs. It also finds applications in the polymer industry, particularly in the synthesis of biodegradable polymers. Additionally, it can be used in sensors for detecting organic compounds and in semiconductor materials for specific electronic applications.
What precautions should be taken when handling 3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 747353-15-7)?
When handling 3-Methyl-3H-spiro[2-benzofuran-1,4'-piperidine], it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood to avoid exposure. In case of a spill, neutralize the compound with a suitable agent and clean up using appropriate procedures. Always consult the safety data sheet (SDS) for detailed information on handling and disposal.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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