2-(4,5-dihydro-1H-imidazol-2-yl)pyridine

Basic Information

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CAS Number

7471-05-8

Molecular Formula

C8H9N3

Molecular Weight

147.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

104-105 ºC

Boiling Point

172-173 ºC (6 Torr)

Density

1.24±0.1 g/cm3 (20 ºC 760 Torr),

Flash Point

121.8±25.1 ºC,

SMILES

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C1CN=C(N1)C2=CC=CC=N2

InChI

InChI=1S/C8H9N3/c1-2-4-9-7(3-1)8-10-5-6-11-8/h1-4H,5-6H2,(H,10,11)

InChIKey

BPPSPXOWNGOEGL-UHFFFAOYSA-N

LogP

0.43140000000000006

Topological Polar Surface Area

37.28 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

165

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

DS-16905
2-(4,5-Dihydro-1H-imidazol-2-yl)-pyridine
2-(2'-pyridyl)imidazoline
NSC403538
NSC-403538
CHEMBL13862
Z1198221938
Pyridine, 2-(4,5-dihydro-1H-imidazol-2-yl)-
CS-W018360
7471-05-8
BDBM50240368
BPPSPXOWNGOEGL-UHFFFAOYSA-N
EN300-103282
SCHEMBL1345182
MFCD09743888
AKOS000361803
O10472
2-(2-Pyridyl)-imidazoline
DTXSID10323297
F2197-0086
2-(4,5-dihydro-1H-imidazol-2-yl)pyridine
2-(4,5-Dihydro-1H-imidazol-2-yl)pyridine
2-(4,5-dihydro-1H-imidazol-2-yl)-pyridine
2-(2-Pyridyl)imidazoline
2,2'-pyridyl imidazoline
2-{pyridyl-(2)}-imidazoline
4,5-dihydro-2-(pyridin-2-yl)-1H-imidazole
AC1L83HB
ANW-71690
CHEBI:113262
CTK8C4374

MDL Number

MFCD09743888

FAQ

What are the physical and chemical properties of 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine (CAS: 7471-05-8)?

2-(4,5-dihydro-1H-imidazol-2-yl)pyridine is a solid, crystalline compound with a molecular weight of approximately 172.17 g/mol. It has limited solubility in water but is more soluble in common organic solvents such as ethanol and acetone. Chemically, it is stable under normal conditions but can react with strong acids or bases. It is used in various applications due to its unique chemical properties and biological activity.

How is 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine (CAS: 7471-05-8) typically synthesized?

2-(4,5-dihydro-1H-imidazol-2-yl)pyridine is typically synthesized through a multi-step process involving the reaction of 2-bromopyridine with 2,5-dihydroxy-4-imidazole, followed by a reduction step. The synthesis requires careful control of reaction conditions to achieve high yield and selectivity. Common solvents include toluene and acetic acid, with the use of palladium catalysts for efficient imidazolization. Yield and purity can be optimized through purification techniques such as recrystallization.

What industries use 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine (CAS: 7471-05-8)?

2-(4,5-dihydro-1H-imidazol-2-yl)pyridine is used in several industries, including pharmaceuticals, where it serves as a key intermediate in the synthesis of drugs. It also finds applications in the polymer industry for the development of advanced materials, and in the semiconductor industry for electronic applications. Additionally, it is used in the production of sensors for detecting various chemical species.

What precautions should be taken when handling 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine (CAS: 7471-05-8)?

When handling 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine (CAS: 7471-05-8), it is important to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and strong oxidizers. Fume hoods should be used during handling to minimize exposure. In case of spillage, it should be cleaned up using appropriate safety protocols, and the incident should be reported to the safety officer. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.