Compound Q&A

How is 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine (CAS: 7471-05-8) typically synthesized?

Answer

2-(4,5-dihydro-1H-imidazol-2-yl)pyridine
2-(4,5-dihydro-1H-imidazol-2-yl)pyridine is typically synthesized through a multi-step process involving the reaction of 2-bromopyridine with 2,5-dihydroxy-4-imidazole, followed by a reduction step. The synthesis requires careful control of reaction conditions to achieve high yield and selectivity. Common solvents include toluene and acetic acid, with the use of palladium catalysts for efficient imidazolization. Yield and purity can be optimized through purification techniques such as recrystallization.

About

CAS No 7471-05-8
English Name 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine
Molecular Formula C8H9N3
Molecular Weight 147.18 g/mol
SMILES C1CN=C(N1)C2=CC=CC=N2
InChIKey BPPSPXOWNGOEGL-UHFFFAOYSA-N
Last Updated: 2025-11-08 00:00

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