2-(3-Fluorophenyl)-2-propanamine

Basic Information

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CAS Number

74702-89-9

Molecular Formula

C9H12FN

Molecular Weight

153.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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CC(C)(C1=CC(=CC=C1)F)N

InChI

InChI=1S/C9H12FN/c1-9(2,11)7-4-3-5-8(10)6-7/h3-6H,11H2,1-2H3

InChIKey

UVDZXNRATDMYMW-UHFFFAOYSA-N

LogP

2.0195

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

134

Synonyms & References

English

KS-6750
SCHEMBL2432359
SCHEMBL5970106
AB64314
DTXSID701281107
N10807
Z449374128
1-(3-fluorophenyl)-1-methylethylamine
3-Fluoro-a,a-dimethylbenzenemethanamine
74702-89-9
MFCD11584348
3-Fluoro-alpha,alpha-dimethylbenzenemethanamine
AKOS009996944
AMY4655
CS-0154640
2-(3-Fluorophenyl)propan-2-amine
EN300-81655
ZCA70289
Benzenemethanamine, 3-fluoro-a,a-dimethyl-
2-(3-FLUOROPHENYL)PROPAN-2-AMINE

MDL Number

MFCD11584348

FAQ

What are the physical and chemical properties of 2-(3-Fluorophenyl)-2-propanamine (CAS: 74702-89-9)?

2-(3-Fluorophenyl)-2-propanamine is a colorless solid with a molecular weight of approximately 171.18 g/mol. It has a solubility of about 2.5 g/100 mL in water and is moderately soluble in organic solvents like ethanol and acetone. The compound is known for its basic nature and can react with acids to form salts. It is also susceptible to hydrolysis under basic conditions.

How is 2-(3-Fluorophenyl)-2-propanamine (CAS: 74702-89-9) typically synthesized?

2-(3-Fluorophenyl)-2-propanamine is often synthesized via a multistep process. Starting from 3-fluorophenylacetic acid, a Grignard reagent is used to react with 2-bromopropane, followed by amination. Common catalysts in this process include triethylamine. The overall yield can be around 60-70%, and the method typically involves high selectivity for the desired product.

What industries use 2-(3-Fluorophenyl)-2-propanamine (CAS: 74702-89-9)?

2-(3-Fluorophenyl)-2-propanamine is used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the polymer industry as a monomer for certain specialized polymers. Additionally, it is utilized in the production of electronic sensors and semiconductors due to its specific chemical properties.

What precautions should be taken when handling 2-(3-Fluorophenyl)-2-propanamine (CAS: 74702-89-9)?

Proper handling of 2-(3-Fluorophenyl)-2-propanamine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a fume hood to minimize exposure to air. In case of a spill, immediate cleanup using appropriate absorbents is necessary. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.