Compound Q&A

How is 2-(3-Fluorophenyl)-2-propanamine (CAS: 74702-89-9) typically synthesized?

Answer

2-(3-Fluorophenyl)-2-propanamine
2-(3-Fluorophenyl)-2-propanamine is often synthesized via a multistep process. Starting from 3-fluorophenylacetic acid, a Grignard reagent is used to react with 2-bromopropane, followed by amination. Common catalysts in this process include triethylamine. The overall yield can be around 60-70%, and the method typically involves high selectivity for the desired product.

About

CAS No 74702-89-9
English Name 2-(3-Fluorophenyl)-2-propanamine
Molecular Formula C9H12FN
Molecular Weight 153.2 g/mol
SMILES CC(C)(C1=CC(=CC=C1)F)N
InChIKey UVDZXNRATDMYMW-UHFFFAOYSA-N
Last Updated: 2026-01-07 14:58

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