1-(tert-Butyldimethylsilyloxy)-2-propanone

Basic Information

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CAS Number

74685-00-0

Molecular Formula

C9H20O2Si

Molecular Weight

188.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Physical Properties

Boiling Point

35-38 °C/0.6 mmHg

Density

0.976 g/mL at 25 °C

Refractive Index

n20/D 1.426(lit.)

SMILES

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CC(=O)CO[Si](C)(C)C(C)(C)C

InChI

InChI=1S/C9H20O2Si/c1-8(10)7-11-12(5,6)9(2,3)4/h7H2,1-6H3

InChIKey

LHYDYTSJUGPFLA-UHFFFAOYSA-N

LogP

2.597200000000001

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

168

Synonyms & References

English

1-{[tert-Butyl(dimethyl)silyl]oxy}propan-2-one
AKOS015913601
[t-butyl(dimethyl)silyloxy]acetone
74685-00-0
MFCD01321330
1-[tert-butyl(dimethyl)silyl]oxypropan-2-one
1-[(tert-Butyldimethylsilyl)oxy]-2-propanone
2-Propanone, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
1-((tert-Butyldimethylsilyl)oxy)propan-2-one
AS-40102
CS-0112903
SCHEMBL1085871
1-{[tert-butyl (dimethyl)silyl]oxy}acetone
1-{[t-butyl(dimethyl)silyl]oxy}-2-propanone
DTXSID90399591
ZCA68500
1-{[tert-butyl(dimethyl)-silyl]oxy}acetone
1-(tert-Butyldimethylsilyloxy)-2-propanone
FT-0649667
1-(tert-Butyldimethylsilyloxy)-2-propanone, 98%
SY043365
LHYDYTSJUGPFLA-UHFFFAOYSA-N
1-(t-butyldimethylsilyloxy)-2-propanone
1-(tert-butyldimethylsilyloxy)propan-2-one
1-(t-BUTYLDIMETHYLSILOXY)-2-PROPANONE
1-[(tert-butyldimethylsilyl)oxy]propan-2-one
2-Propanone,1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
1-(tert-ButyldiMethylsilyloxy)-2-propanone

MDL Number

MFCD01321330

Customs Code

2931900090

FAQ

What regulatory guidelines apply to 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0)?

1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which requires specific hazard communication on labels and safety data sheets. It is also subject to the EU's REACH regulations, which require registration for chemicals manufactured or imported in quantities of 1000 kg or more. Additionally, the FDA and EPA have regulations for the use and disposal of this compound to ensure safety in the manufacturing and handling processes.

Are there alternatives to 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) in synthesis?

Alternatives to 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) include other silyl ethers such as tert-butyldimethylsilyl chloride (TBDMSCl) or trimethylchlorosilane (TMSCl), which can serve similar purposes in organic synthesis. These alternatives may have different reactivity profiles, so careful selection based on the specific reaction conditions is necessary.

What is the market or research trend for 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0)?

The market for 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) is driven by its use in organic synthesis, particularly in protecting groups for functional groups. Research trends are focusing on the development of more efficient and environmentally friendly methods for its synthesis and use. The demand is expected to grow with advancements in pharmaceutical and materials science applications.

How should waste containing 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) be handled?

Waste containing 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) should be collected in appropriate containers and disposed of according to local regulations. Incineration is a common method for its disposal, but it should be conducted in a manner that minimizes environmental impact. Professional waste disposal services are recommended for handling large quantities or hazardous waste to ensure compliance with regulations and environmental safety.