Compound Q&A

Are there alternatives to 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) in synthesis?

Answer

1-(tert-Butyldimethylsilyloxy)-2-propanone
Alternatives to 1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) include other silyl ethers such as tert-butyldimethylsilyl chloride (TBDMSCl) or trimethylchlorosilane (TMSCl), which can serve similar purposes in organic synthesis. These alternatives may have different reactivity profiles, so careful selection based on the specific reaction conditions is necessary.

About

CAS No 74685-00-0
English Name 1-(tert-Butyldimethylsilyloxy)-2-propanone
Molecular Formula C9H20O2Si
Molecular Weight 188.34 g/mol
SMILES CC(=O)CO[Si](C)(C)C(C)(C)C
InChIKey LHYDYTSJUGPFLA-UHFFFAOYSA-N
Last Updated: 2025-10-26 19:35

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