6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine

Basic Information

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CAS Number

746668-59-7

Molecular Formula

C7H6BrN3

Molecular Weight

212.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC1=C(C=CC2=NC=NN12)Br

InChI

InChI=1S/C7H6BrN3/c1-5-6(8)2-3-7-9-4-10-11(5)7/h2-4H,1H3

InChIKey

LYFZTLWVHLYBEK-UHFFFAOYSA-N

LogP

1.8002199999999997

Topological Polar Surface Area

30.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

153

Synonyms & References

English

DTXSID50469709
AKOS015842239
FS-2906
A865833
J-518409
FT-0685668
EN300-1592162
6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine
SCHEMBL5930819
MFCD09038165
6-bromo-5-methyl-[1,2,4]triazolo[1,5-a]pyridine
6-Bromo-5-methyl[1 pound not2 pound not4]triazolo[1 pound not5-a]pyridine
746668-59-7
SY066267
AM20061852
6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine, AldrichCPR
[1,2,4]Triazolo[1,5-a]pyridine,6-bromo-5-methyl-
RP09034
FCH1390749
AX8108511
AB0026535
ST24029682
W8224

MDL Number

MFCD09038165

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine (CAS: 746668-59-7)?

6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine is a solid with a crystalline form. Its molecular weight is approximately 243.04 g/mol. It has low solubility in water but is more soluble in organic solvents like DMF and DMSO. This compound is known for its high reactivity, particularly towards nucleophiles and electrophiles, making it suitable for various synthetic transformations.

How is 6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine (CAS: 746668-59-7) typically synthesized?

6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine is often synthesized via a multi-step process involving the bromination of 5-methyl[1,2,4]triazolo[1,5-a]pyridine followed by amination of the resulting bromide. This synthesis typically requires the use of a catalytic amount of a Lewis acid and a base, yielding a product with a good yield and high selectivity.

What industries use 6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine (CAS: 746668-59-7)?

6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine is primarily used in the pharmaceutical industry for the synthesis of bioactive compounds. It also finds applications in the polymer industry as a precursor for the development of advanced materials and in the semiconductor industry for doping purposes.

What precautions should be taken when handling 6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine (CAS: 746668-59-7)?

Handling 6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyridine should be done with caution. Always wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation of the compound. Spills should be cleaned up using appropriate absorbents, and the area should be flushed with water. Refer to the Safety Data Sheet (SDS) for further details on handling and disposal.