4-chloro-N,N-diethylbenzamide

Basic Information

View in Editor

CAS Number

7461-38-3

Molecular Formula

C11H14ClNO

Molecular Weight

211.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

CCN(CC)C(=O)C1=CC=C(C=C1)Cl

InChI

InChI=1S/C11H14ClNO/c1-3-13(4-2)11(14)9-5-7-10(12)8-6-9/h5-8H,3-4H2,1-2H3

InChIKey

VQIFBGNOSBKNJI-UHFFFAOYSA-N

LogP

2.822000000000001

Topological Polar Surface Area

20.310000000000002 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

184

Synonyms & References

English

NSC-404988
NSC404988
SCHEMBL11809876
BCP32796
NSC404988;NSC 404988;NSC-404988;Benzamide,4-chloro-N,N-diethyl-
VQIFBGNOSBKNJI-UHFFFAOYSA-N
TS-09036
Benzamide (NSC 404988)
4-chloro-N,N-diethylbenzamide
7461-38-3
DTXSID40323846
CS-0319469
AKOS002984968
Benzamide, 4-chloro-N,N-diethyl-
NSC 404988
4-(Et2NOC)C6H4Cl
4-chloro-N,N-diethyl-benzamide
AC1L85KS
KB-110954
N,N-diethyl-4-chlorobenzamide
p-ClC6H4C(O)NEt2
p-ClC6H4CONEt2
p-Et2NC(O)C6H4Cl

MDL Number

MFCD00584080

FAQ

What are the physical and chemical properties of 4-chloro-N,N-diethylbenzamide (CAS: 7461-38-3)?

4-Chloro-N,N-diethylbenzamide (CAS: 7461-38-3) is a white crystalline solid with a molecular weight of approximately 232.63 g/mol. It has a melting point of 62-64°C and is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but can react with strong bases or oxidizing agents to form other chlorobenzamides.

How is 4-chloro-N,N-diethylbenzamide (CAS: 7461-38-3) typically synthesized?

4-Chloro-N,N-diethylbenzamide (CAS: 7461-38-3) is often synthesized by reacting 4-chlorobenzamide with diethylamine in the presence of a catalyst such as triethylamine. The reaction yields a high purity product with good selectivity and a yield of about 85%. The process is conducted in a solvent like acetonitrile at room temperature or slightly elevated temperatures.

What industries use 4-chloro-N,N-diethylbenzamide (CAS: 7461-38-3)?

4-Chloro-N,N-diethylbenzamide (CAS: 7461-38-3) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds application in the polymer industry for modifying polymer properties and in the chemical sensor industry for developing gas sensors. Additionally, it is used in the semiconductor industry for specific applications requiring chlorinated aromatic compounds.

What precautions should be taken when handling 4-chloro-N,N-diethylbenzamide (CAS: 7461-38-3)?

When handling 4-chloro-N,N-diethylbenzamide (CAS: 7461-38-3), it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate methods and proper disposal procedures should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and handling instructions.