4-chloro-N,N-diethylbenzamide(CAS: 7461-38-3)

4-Chloro-N,N-diethylbenzamide (CAS: 7461-38-3) is a white crystalline solid with a molecular weight of approximately 232.63 g/mol. It has a melting point of 62-64°C and is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but can react with strong bases or oxidizing agents to form other chlorobenzamides.

4-Chloro-N,N-diethylbenzamide (CAS: 7461-38-3) is often synthesized by reacting 4-chlorobenzamide with diethylamine in the presence of a catalyst such as triethylamine. The reaction yields a high purity product with good selectivity and a yield of about 85%. The process is conducted in a solvent like acetonitrile at room temperature or slightly elevated temperatures.

4-Chloro-N,N-diethylbenzamide (CAS: 7461-38-3) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds application in the polymer industry for modifying polymer properties and in the chemical sensor industry for developing gas sensors. Additionally, it is used in the semiconductor industry for specific applications requiring chlorinated aromatic compounds.

When handling 4-chloro-N,N-diethylbenzamide (CAS: 7461-38-3), it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate methods and proper disposal procedures should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and handling instructions.