3,5-Difluoro-2-pyridinecarboxylic acid

Basic Information

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CAS Number

745784-04-7

Molecular Formula

C6H3F2NO2

Molecular Weight

159.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

203-208 °C

Boiling Point

240.6°C at 760 mmHg

Density

1.535

Flash Point

240.6 °C at 760 mmHg

Refractive Index

1.515

SMILES

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C1=C(C=NC(=C1F)C(=O)O)F

InChI

InChI=1S/C6H3F2NO2/c7-3-1-4(8)5(6(10)11)9-2-3/h1-2H,(H,10,11)

InChIKey

QKLXAJQKMIWFRC-UHFFFAOYSA-N

LogP

1.058

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

165

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Pyridinecarboxylic acid, 3,5-difluoro-
3,5-Difluoro-2-pyridinecarboxylic acid
MFCD05664124
DTXSID90382544
3,5-difluoro-pyridine-2-carboxylic acid
SB40501
SY008959
FT-0649906
SCHEMBL107357
Z1201623169
745784-04-7
QKLXAJQKMIWFRC-UHFFFAOYSA-N
3,5-difluoropicolinic acid
3,5-Difluoropicolinicacid
CS-W007725
A9547
EN300-98146
AM62409
3 pound not5-Difluoropyridine-2-carboxylicacid
PS-6373
3,5-Difluoropyridine-2-carboxylic acid, 95%
3,5-difluoropyridine-2-carboxylic Acid
J-511332
AKOS005256446
3,5-Difluoropicolinic acid
3,5-Difluoropyridine-2-carboxylic acid
3,5-difluoro-2-Pyridinecarboxylic acid
C6H3F2NO2
3,5-Difluoro-2-pyridinecarboxylicacid
2-Carboxy-3,5-difluoropyridine
STL554748

MDL Number

MFCD05664124

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3,5-Difluoro-2-pyridinecarboxylic acid (CAS: 745784-04-7)?

3,5-Difluoro-2-pyridinecarboxylic acid is a white crystalline solid with a molecular weight of 163.07 g/mol. It has a melting point of 215-216°C. The compound is moderately soluble in water and ethanol. It is chemically stable but reactive towards bases and nucleophiles. For accurate handling, ensure appropriate safety measures are in place.

How is 3,5-Difluoro-2-pyridinecarboxylic acid (CAS: 745784-04-7) typically synthesized?

3,5-Difluoro-2-pyridinecarboxylic acid is commonly synthesized through the oxidation of 2,5-difluoropyridine with peroxyacetic acid, followed by hydrolysis. This method provides a high yield and good selectivity. The reaction is typically conducted in a controlled environment to ensure safety and efficacy.

What industries use 3,5-Difluoro-2-pyridinecarboxylic acid (CAS: 745784-04-7)?

3,5-Difluoro-2-pyridinecarboxylic acid is used in pharmaceuticals for the synthesis of drugs, in polymers for functionalizing materials, in sensor technology for detecting specific analytes, and in semiconductor manufacturing for etching processes. Its unique chemical structure makes it valuable in these applications.

What precautions should be taken when handling 3,5-Difluoro-2-pyridinecarboxylic acid (CAS: 745784-04-7)?

When handling 3,5-Difluoro-2-pyridinecarboxylic acid, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risk. Store the compound in a cool, dry place away from heat sources. In case of spill, follow the safety data sheet (SDS) guidelines for appropriate disposal and clean-up procedures.