3,5-Difluoro-2-pyridinecarboxylic acid(CAS: 745784-04-7)

3,5-Difluoro-2-pyridinecarboxylic acid is a white crystalline solid with a molecular weight of 163.07 g/mol. It has a melting point of 215-216°C. The compound is moderately soluble in water and ethanol. It is chemically stable but reactive towards bases and nucleophiles. For accurate handling, ensure appropriate safety measures are in place.

3,5-Difluoro-2-pyridinecarboxylic acid is commonly synthesized through the oxidation of 2,5-difluoropyridine with peroxyacetic acid, followed by hydrolysis. This method provides a high yield and good selectivity. The reaction is typically conducted in a controlled environment to ensure safety and efficacy.

3,5-Difluoro-2-pyridinecarboxylic acid is used in pharmaceuticals for the synthesis of drugs, in polymers for functionalizing materials, in sensor technology for detecting specific analytes, and in semiconductor manufacturing for etching processes. Its unique chemical structure makes it valuable in these applications.

When handling 3,5-Difluoro-2-pyridinecarboxylic acid, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risk. Store the compound in a cool, dry place away from heat sources. In case of spill, follow the safety data sheet (SDS) guidelines for appropriate disposal and clean-up procedures.