1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene

Basic Information

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CAS Number

74483-51-5

Molecular Formula

C8H5Cl2F3

Molecular Weight

229.03 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC1=CC(=C(C=C1C(F)(F)F)Cl)Cl

InChI

InChI=1S/C8H5Cl2F3/c1-4-2-6(9)7(10)3-5(4)8(11,12)13/h2-3H,1H3

InChIKey

OARYHYOOIUIKFZ-UHFFFAOYSA-N

LogP

4.320620000000001

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

181

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

PS-11543
74483-51-5
4,5-Dichloro-2-methylbenzotrifluoride
A25096
1,2-dichloro-4-methyl-5-(trifluoromethyl)benzene
Benzene, 1,2-dichloro-4-methyl-5-(trifluoromethyl)-
AMY7602
MFCD06246858
(2-PHENOXYETHYLTHIO)ACETICACIDHYDRAZIDE
AKOS005762913
3,4-DICHLORO-6-(TRIFLUOROMETHYL)TOLUENE
CS-0317213
4,5-Dichloro-2-(trifluoromethyl)toluene;3,4-Dichloro-6-trifluoromethyltoluene
SCHEMBL8915338
DTXSID20408923
3,4-DICHLORO-6-METHYLBENZOTRIFLUORIDE
FT-0641523
OARYHYOOIUIKFZ-UHFFFAOYSA-N
4,5-Dichloro-2-methyltrifluorotoluene
AC-24749
1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene
3,4-Dichloro-6-trifluoromethyltoluene
BENZENE, 1,2-DICHLORO-4-METHYL-5-(TRIFLUOROMETHYL)-
4,5-Dichloro-2-Trifluoromethyl Toluene
3,4-Dichloro-6-(trifluoromethyl)toluene

MDL Number

MFCD06246858

Customs Code

2903999090

FAQ

What are the physical and chemical properties of 1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene (CAS: 74483-51-5)?

1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene is a viscous liquid at room temperature with a molecular weight of approximately 257.03 g/mol. It has a limited solubility in water but is highly soluble in organic solvents. Chemically, it is relatively stable but can undergo substitution reactions, particularly with nucleophiles. It has a distinct odor and is flammable.

How is 1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene (CAS: 74483-51-5) typically synthesized?

1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene is synthesized via Friedel-Crafts alkylation and electrophilic aromatic substitution reactions. Commonly, it is prepared from benzene, methyl triflate, and chlorine in the presence of aluminum chloride as a catalyst. The reaction is conducted under anhydrous conditions and requires careful control of temperature and reagent ratios to achieve high selectivity and yield.

What industries use 1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene (CAS: 74483-51-5)?

1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene finds applications in various industries, including pharmaceuticals, where it is used as an intermediate in the synthesis of certain drugs. It is also utilized in the production of polymers and electronic materials due to its functional groups which can be further modified to enhance material properties.

What precautions should be taken when handling 1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene (CAS: 74483-51-5)?

When handling 1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. This compound should be stored in a cool, dry place, away from sources of heat and ignition. It is flammable and toxic, so work should be conducted in a fume hood. In case of spill, immediately evacuate the area and clean up using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.