1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one

Basic Information

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CAS Number

7397-68-4

Molecular Formula

C6H5N3O

Molecular Weight

135.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C1=CN=CC2=C1NC(=O)N2

InChI

InChI=1S/C6H5N3O/c10-6-8-4-1-2-7-3-5(4)9-6/h1-3H,(H2,8,9,10)

InChIKey

ZJSVBILSBHWRTN-UHFFFAOYSA-N

LogP

0.2512

Topological Polar Surface Area

61.54 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

159

Synonyms & References

English

AKOS022421475
EN300-250361
DS-7342
7397-68-4
FT-0695440
1H-Imidazo[4 pound not5-c]pyridin-2(3H)-one
CS1977
SY007152
AB11607
Oprea1_778542
1,3-Dihydro-2h-imidazo[4,5-c]pyridin-2-one
F8883-4839
2H-Imidazo[4,5-c]pyridin-2-one, 1,3-dihydro-
1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE
F0378-0007
AMY5710
MFCD18872694
SCHEMBL259923
1h-imidazo[4,5-c]pyridin-2-ol
AC-31817
1,3-dihydroimidazo[4,5-c]pyridin-2-one
AKOS013060249
1H,2H,3H-imidazo[4,5-c]pyridin-2-one
ZJSVBILSBHWRTN-UHFFFAOYSA-N
CS-W021327
3H-imidazo[4,5-c]pyridin-2-ol
1,3-dihydro-2h-imidazo[4,5-c]pyridin-2-one
3H-Imidazo[4,5-c]pyridin-2-ol
1,3-dihydro-2H-imidazo<4,5-c>pyridin-2-one
1H-Imidazo[4,5-c]pyridin-2(3H)-one
5-AZOBENZIMIDAZOLONE

MDL Number

MFCD18872694

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one (CAS: 7397-68-4)?

1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one is a white to off-white crystalline solid with a molecular weight of approximately 146.12 g/mol. It is slightly soluble in water but soluble in organic solvents such as ethanol and acetone. Chemically, it is stable under normal conditions, but it can react with strong bases and acids. It has a pKa of about 5.5 and exhibits basic properties.

How is 1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one (CAS: 7397-68-4) typically synthesized?

1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one is commonly synthesized via the condensation of 2-amino-4,5-dihydroimidazole with acetylacetone. The reaction is typically carried out in the presence of a base such as sodium hydroxide or potassium hydroxide, yielding the product with good selectivity and moderate to high yields. Post-synthesis, it can be purified using column chromatography.

What industries use 1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one (CAS: 7397-68-4)?

1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one is used in pharmaceuticals for its potential as a precursor in the synthesis of drug candidates. It also finds applications in the polymer industry as a stabilizer and in sensor technology for its ability to act as a pH indicator. Additionally, it is used in the semiconductor industry as a dopant.

What precautions should be taken when handling 1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one (CAS: 7397-68-4)?

When handling 1,3-Dihydro-2H-imidazo[4,5-c]pyridin-2-one, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from strong acids and bases. In case of a spill, it should be cleaned up using absorbent material and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.