Butyl glycolate

Basic Information

View in Editor

CAS Number

7397-62-8

Molecular Formula

C6H12O3

Molecular Weight

132.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

-26 °C

Boiling Point

187-190 °C

Density

1.019 g/mL at 20 °C

Refractive Index

n20/D 1.427

SMILES

View in Editor

CCCCOC(=O)CO

InChI

InChI=1S/C6H12O3/c1-2-3-4-9-6(8)5-7/h7H,2-5H2,1H3

InChIKey

VFGRALUHHHDIQI-UHFFFAOYSA-N

LogP

0.322

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

80.4

Safety Information

View Safety Information

Hazard Statement

H318 Causes serious eye damage
Serious eye damage/eye irritation

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

Butyl glycolate
Butyl hydroxyacetate
Acetic acid, hydroxy-, butyl ester
Buthyl Glycolate
butyl glycollate
Glycol acid-n-butylester
Glycolic acid, n-butyl ester
Glycolsure-n-butylester
Hydroxyacetic acid, n-butyl ester
hydroxy-aceticacibutylester
hydroxyaceticacidbutylester
N-BUTYL GLYCOLATE
n-Butyl hydroxyacetate
butyl 2-hydroxyacetate
glycolic acid butyl ester
3H5QAS0HZX
Acetic acid, 2-hydroxy-, butyl ester
VFGRALUHHHDIQI-UHFFFAOYSA-N
Polysolvan 0
Butylglykolat
Butyl hydroxyacetate #
DSSTox_RID_80425
DSSTox_CID_24725
DSSTox_GSID_44725
KSC492O7L

MDL Number

MFCD00042732

FAQ

What are the physical and chemical properties of Butyl glycolate (CAS: 7397-62-8)?

Butyl glycolate (CAS: 7397-62-8) is a colorless liquid with a fruity odor. Its molecular weight is approximately 144.19 g/mol and it has a high solubility in water and most organic solvents. It is slightly soluble in ethanol and poorly soluble in ether. Butyl glycolate is reactive towards hydrolysis and acidic catalysts, making it susceptible to breakdown in aqueous environments.

How is Butyl glycolate (CAS: 7397-62-8) typically synthesized?

Butyl glycolate is typically synthesized by the esterification of butyric acid with glycolic acid in the presence of a catalyst such as sulfuric acid or phosphoric acid. The reaction is carried out under reflux conditions, and the product is isolated by distillation. The yield and selectivity are influenced by the reaction conditions and the choice of catalyst.

What industries use Butyl glycolate (CAS: 7397-62-8)?

Butyl glycolate (CAS: 7397-62-8) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, as a plasticizer in polymer production, in the formulation of adhesives and coatings, and as a component in sensors and semiconductors for its solubilizing and reactive properties.

What precautions should be taken when handling Butyl glycolate (CAS: 7397-62-8)?

When handling Butyl glycolate (CAS: 7397-62-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat sources and incompatible materials. Use a fume hood during operations to minimize exposure. In case of a spill, neutralize the spill with an appropriate chemical neutralizer and clean up according to the Safety Data Sheet (SDS).