6-bromo-4-methyl-pyridin-2-amine

Basic Information

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CAS Number

73895-98-4

Molecular Formula

C6H7BrN2

Molecular Weight

187.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC1=CC(=NC(=C1)Br)N

InChI

InChI=1S/C6H7BrN2/c1-4-2-5(7)9-6(8)3-4/h2-3H,1H3,(H2,8,9)

InChIKey

ABYCTYJDRLQBMT-UHFFFAOYSA-N

LogP

1.7347199999999998

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

97.1

Synonyms & References

English

2-Amino-6-bromo-4-picoline
73895-98-4
6-Bromo-4-methylpyridin-2-amine
6-amino-2-bromo-4-methylpyridine
CS-0043073
2-bromo-4-methyl-6-aminopyridine
6-bromo-4-methyl-2-pyridinamine
EN300-114620
AM62482
DTXSID80623256
ABYCTYJDRLQBMT-UHFFFAOYSA-N
SCHEMBL2228056
6-bromo-4-methylpyridine-2-amine
AS-813/43501672
2-AMINO-6-BROMO-4-METHYL PYRIDINE
SB13711
6-Bromo-4-methyl-pyridin-2-ylamine
2-bromo4-methyl-6-aminopyridine
SY105075
2-Bromoo-4-methyl-6-aminopyridine
W-203685
6-bromo-4-methyl pyridine-2-amine
2-Amino-4-methyl-6-bromopyridine
DS-11875
2-Pyridinamine, 6-bromo-4-methyl-
2-Amino-6-bromo-4-methylpyridine
MFCD11036206
2-Bromo-2-hydroxylacetophenone
AKOS006307539
2-BROMOO-4-METHYL-6-AMINOPYRIDINE
2-Pyridinamine,6-bromo-4-methyl-

MDL Number

MFCD11036206

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-bromo-4-methyl-pyridin-2-amine (CAS: 73895-98-4)?

6-Bromo-4-methyl-pyridin-2-amine is a crystalline solid with a molecular weight of approximately 216.03 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and dichloromethane. The compound is moderately reactive, particularly with nucleophiles. It forms a stable crystalline form under typical storage conditions.

How is 6-bromo-4-methyl-pyridin-2-amine (CAS: 73895-98-4) typically synthesized?

6-Bromo-4-methyl-pyridin-2-amine is commonly synthesized via the amination of 4-methyl-6-bromopyridine with an amine reagent in the presence of a suitable base and a catalyst. The reaction typically proceeds with high selectivity and yields up to 90% of the desired product.

What industries use 6-bromo-4-methyl-pyridin-2-amine (CAS: 73895-98-4)?

6-Bromo-4-methyl-pyridin-2-amine is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also has applications in the polymer industry for the development of certain functional materials and in sensors for its unique reactivity. Its potential in semiconductors is also being explored.

What precautions should be taken when handling 6-bromo-4-methyl-pyridin-2-amine (CAS: 73895-98-4)?

When handling 6-bromo-4-methyl-pyridin-2-amine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to minimize exposure. Spills should be carefully cleaned up and disposed of according to the Material Safety Data Sheet (MSDS) guidelines. Always consult the latest SDS for detailed safety information.