6-bromo-4-methyl-pyridin-2-amine(CAS: 73895-98-4)

6-Bromo-4-methyl-pyridin-2-amine is a crystalline solid with a molecular weight of approximately 216.03 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and dichloromethane. The compound is moderately reactive, particularly with nucleophiles. It forms a stable crystalline form under typical storage conditions.

6-Bromo-4-methyl-pyridin-2-amine is commonly synthesized via the amination of 4-methyl-6-bromopyridine with an amine reagent in the presence of a suitable base and a catalyst. The reaction typically proceeds with high selectivity and yields up to 90% of the desired product.

6-Bromo-4-methyl-pyridin-2-amine is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also has applications in the polymer industry for the development of certain functional materials and in sensors for its unique reactivity. Its potential in semiconductors is also being explored.

When handling 6-bromo-4-methyl-pyridin-2-amine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to minimize exposure. Spills should be carefully cleaned up and disposed of according to the Material Safety Data Sheet (MSDS) guidelines. Always consult the latest SDS for detailed safety information.