2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate

Basic Information

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CAS Number

73889-19-7

Molecular Formula

C17H26N2O2

Molecular Weight

290.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

122-125 ºC

Boiling Point

400.9 °C at 760 mmHg

Density

1.07

Flash Point

196.2 °C

Refractive Index

1.542

SMILES

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CC(C)(C)OC(=O)NC1CCN(CC1)CC2=CC=CC=C2

InChI

InChI=1S/C17H26N2O2/c1-17(2,3)21-16(20)18-15-9-11-19(12-10-15)13-14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H,18,20)

InChIKey

WFKLUNLIZMWKNF-UHFFFAOYSA-N

LogP

3.1757000000000017

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

324

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DS-11141
1-Benzyl-4-tertbutyloxycarbonylaminopiperidine
tert-butyl 1-benzyl-4-piperidinylcarbamate
FT-0649672
1-benzyl-4-(tert-butoxycarbonylamino)piperidine
Z648897674
SY003281
DTXSID30403308
SCHEMBL915402
MFCD03093979
1-Benzyl-4-(Boc-amino)piperidine
AM85351
1-Benzyl-4-t-butyloxycarbonylaminopiperidine
1-Benzyl-4-(N-Boc-amino)piperidine
Carbamic acid, [1-(phenylmethyl)-4-piperidinyl]-, 1,1-dimethylethyl ester
AKOS009318776
tert-Butyl(1-benzylpiperidin-4-yl)carbamate
tert-butyl 1-benzylpiperidin-4-ylcarbamate
YCA88919
1-Benzyl-4-[(tert.-butyloxycarbonyl)amino]-piperidine
1-Benzyl-4-(N-Boc-amino) piperidine
(1-Benzyl-piperidin-4-yl)carbamic acid tert-butyl ester
AC-28088
[1-(Phenylmethyl)-4-piperidinyl]carbamic acid, 1,1-dimethylethyl ester
O-tert-butyl N-(1-benzylpiperidin-4-yl)carbamate
CS-W012193
t-butyl-1-benzylpiperidin-4-ylcarbamate
4-BOC-AMINO-1-BENZYLPIPERIDINE
1-benzyl-4-tert-butoxycarbonylaminopiperidine
WFKLUNLIZMWKNF-UHFFFAOYSA-N
EN300-100537

MDL Number

MFCD03093979

Customs Code

29333990

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate (CAS: 73889-19-7)?

2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate is a crystalline solid with a molecular weight of approximately 363.4 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive due to the presence of the carbamate functional group. It does not have strong odor or taste and is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is 2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate (CAS: 73889-19-7) typically synthesized?

2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate can be synthesized using a multi-step process involving the coupling of 2-methyl-2-propanol and 1-benzyl-4-piperidone in the presence of a catalytic amount of a strong base like sodium hydride. The reaction is carried out in a polar aprotic solvent like N,N-dimethylformamide (DMF) at room temperature, yielding the target compound with good selectivity and a high yield of up to 85%.

What industries use 2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate (CAS: 73889-19-7)?

2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also explored in the polymer industry for its potential as a cross-linking agent, and in sensor technologies for its reactivity with specific analytes. Its applications in semiconductor industries are limited but are being researched for potential use in certain processing steps.

What precautions should be taken when handling 2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate (CAS: 73889-19-7)?

When handling 2-Methyl-2-propanyl (1-benzyl-4-piperidinyl)carbamate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of any vapors. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always consult the Safety Data Sheet (SDS) for detailed information on handling and disposal procedures.