trans-4-Methoxycyclohexanecarboxylic acid

Basic Information

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CAS Number

73873-61-7

Molecular Formula

C8H14O3

Molecular Weight

158.2 g/mol

Basic Physical Properties

SMILES

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COC1CCC(CC1)C(=O)O

InChI

InChI=1S/C8H14O3/c1-11-7-4-2-6(3-5-7)8(9)10/h6-7H,2-5H2,1H3,(H,9,10)/t6-,7-

InChIKey

WKILSRYNRQGRMA-LJGSYFOKSA-N

LogP

1.2762

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

136

Synonyms & References

English

MFCD27928131
SB15661
SCHEMBL1979948
YCA87361
4-methoxy-cyclohexane carboxylic acid
SY099517
EN300-6770565
Cyclohexanecarboxylic acid, 4-methoxy-, cis-
73873-61-7
YCA87359
AMY35736
4-METHOXYCYCLOHEXANECARBOXYLIC ACID
95233-12-8
AKOS027336855
4-methoxycylcohexanecarboxylic acid
4-Methoxycyclohexanoic acid
VDA23312
AKOS015894344
WKILSRYNRQGRMA-LJGSYFOKSA-N
Cyclohexanecarboxylicacid,4-methoxy-
SB15662
EN300-107566
Trans-4-methoxycyclohexane carboxylic acid
TS-02102
MFCD20488929
DTXSID801347396
CS-0054432
P15709
rac-(1s,4s)-4-methoxycyclohexane-1-carboxylic
AS-52811
trans-4-methoxycyclohexanecarboxylic acid

MDL Number

MFCD20488929

FAQ

What are the physical and chemical properties of trans-4-Methoxycyclohexanecarboxylic acid (CAS: 73873-61-7)?

Trans-4-Methoxycyclohexanecarboxylic acid is a colorless solid with a molecular weight of approximately 166.17 g/mol. It has a melting point of 71-73°C and a solubility of 0.8 g/L in water. It is moderately reactive, particularly in acidic conditions, and can form esters and anhydrides. It is insoluble in most organic solvents but soluble in water and polar solvents.

How is trans-4-Methoxycyclohexanecarboxylic acid (CAS: 73873-61-7) typically synthesized?

Trans-4-Methoxycyclohexanecarboxylic acid is typically synthesized by the methylation of cyclohexanecarboxylic acid using methanol and an acid catalyst such as sulfuric acid. The reaction is carried out under mild conditions, and the desired trans isomer can be obtained with high selectivity. The yield is generally around 75-85%.

What industries use trans-4-Methoxycyclohexanecarboxylic acid (CAS: 73873-61-7)?

Trans-4-Methoxycyclohexanecarboxylic acid is used in the pharmaceutical industry as a precursor for drug synthesis, in the polymer industry for the production of functionalized polymers, and in the sensor industry for the development of gas-sensitive materials. It is also used in the semiconductor industry for photolithography processes.

What precautions should be taken when handling trans-4-Methoxycyclohexanecarboxylic acid (CAS: 73873-61-7)?

When handling trans-4-Methoxycyclohexanecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be ventilated. It is advisable to consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.