Compound Q&A

How is trans-4-Methoxycyclohexanecarboxylic acid (CAS: 73873-61-7) typically synthesized?

Answer

trans-4-Methoxycyclohexanecarboxylic acid
Trans-4-Methoxycyclohexanecarboxylic acid is typically synthesized by the methylation of cyclohexanecarboxylic acid using methanol and an acid catalyst such as sulfuric acid. The reaction is carried out under mild conditions, and the desired trans isomer can be obtained with high selectivity. The yield is generally around 75-85%.

About

CAS No 73873-61-7
English Name trans-4-Methoxycyclohexanecarboxylic acid
Molecular Formula C8H14O3
Molecular Weight 158.2 g/mol
SMILES COC1CCC(CC1)C(=O)O
InChIKey WKILSRYNRQGRMA-LJGSYFOKSA-N
Last Updated: 2025-11-08 00:00

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