4-Methyl-N-(4-nitrophenyl)benzenesulfonamide | CAS No. 734-25-8

4-Methyl-N-(4-nitrophenyl)benzenesulfonamide

Basic Information

CAS Number

734-25-8

Molecular Formula

C13H12N2O4S

Molecular Weight

292.31 g/mol

AD

Basic Physical Properties

Melting Point

191 °C

CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)[N+](=O)[O-]

InChI

InChI=1S/C13H12N2O4S/c1-10-2-8-13(9-3-10)20(18,19)14-11-4-6-12(7-5-11)15(16)17/h2-9,14H,1H3

InChIKey

ACOIHAFYVPPSOZ-UHFFFAOYSA-N

LogP

4.38100

Complexity

424

Synonyms & References

English

  • D91753
  • p-Toluenesulfonanilide, 4'-nitro-
  • 4'-Nitro-p-toluenesulphonanilide
  • LS-07407
  • SCHEMBL6577363
  • SR-01000252580-1
  • NSC49573
  • J9ZZ3TP9ZJ
  • NSC-49573
  • SR-01000252580
  • 4-Methyl-N-(4-nitrophenyl)benzenesulphonamide
  • BDBM237305
  • NSC 49573
  • n-(4-nitrophenyl)-4-methylbenzenesulphonamide
  • CS-0317221
  • Benzenesulfonamide, 4-methyl-N-(4-nitrophenyl)-
  • DTXSID2061064
  • N-(p-Nitrophenyl)-p-toluenesulphonamide
  • N0632
  • EINECS 211-994-2
  • 4-Methyl-N-(4-nitrophenyl)benzenesulfonamide
  • 4-Methyl-N-(4-nitrophenyl) benzenesulfonamide (11)
  • p-Toluenesulphonanilide, 4'-nitro-
  • 734-25-8
  • 4-methyl-N-(4-nitrophenyl)benzene-1-sulfonamide
  • N-(4-toluenesulfonyl)-4-nitroaniline
  • AKOS003239072
  • N-(4-Nitrophenyl)-4-methylbenzenesulfonamide
  • FT-0632889
  • UNII-J9ZZ3TP9ZJ
  • A837828

MDL Number

MFCD00129916

Customs Code

2935009090

FAQ

What are the physical and chemical properties of 4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8)?

4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8) is a crystalline solid with a molecular weight of approximately 264.17 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. The compound is relatively stable under normal conditions but can react with strong bases. It has a pKa of approximately 7.5, indicating it can act as a weak acid.

How is 4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8) typically synthesized?

4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8) is typically synthesized via the reaction of 4-nitrophenylamine with benzenesulfonyl chloride in the presence of a base such as triethylamine. The reaction is carried out at room temperature and yields a high purity product with good selectivity and high yield.

What industries use 4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8)?

4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8) is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in the polymer industry for the preparation of functional polymers. It has also found applications in the development of sensors and as a reagent in semiconductor manufacturing processes.

What precautions should be taken when handling 4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8)?

When handling 4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat sources and strong oxidizers. Ensure good ventilation and use a fume hood during preparation. In case of spill, do not use a dry sweep method; instead, use a wet mop or absorbent material to prevent dust. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.

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