4-Methyl-N-(4-nitrophenyl)benzenesulfonamide(CAS: 734-25-8)

4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8) is a crystalline solid with a molecular weight of approximately 264.17 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. The compound is relatively stable under normal conditions but can react with strong bases. It has a pKa of approximately 7.5, indicating it can act as a weak acid.

4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8) is typically synthesized via the reaction of 4-nitrophenylamine with benzenesulfonyl chloride in the presence of a base such as triethylamine. The reaction is carried out at room temperature and yields a high purity product with good selectivity and high yield.

4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8) is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in the polymer industry for the preparation of functional polymers. It has also found applications in the development of sensors and as a reagent in semiconductor manufacturing processes.

When handling 4-Methyl-N-(4-nitrophenyl)benzenesulfonamide (CAS: 734-25-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat sources and strong oxidizers. Ensure good ventilation and use a fume hood during preparation. In case of spill, do not use a dry sweep method; instead, use a wet mop or absorbent material to prevent dust. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.