5-Formyl-2-hydroxybenzonitrile

Basic Information

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CAS Number

73289-79-9

Molecular Formula

C8H5NO2

Molecular Weight

147.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C1=CC(=C(C=C1C=O)C#N)O

InChI

InChI=1S/C8H5NO2/c9-4-7-3-6(5-10)1-2-8(7)11/h1-3,5,11H

InChIKey

PWQHSYDCGDVARU-UHFFFAOYSA-N

Complexity

194

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Benzonitrile,5-formyl-2-hydroxy-
A920292
3-Cyano-4-hydroxybenzaldehyde
CS-13170
1,4-Cyclohexadiene-1-carbonitrile, 3-(hydroxymethylene)-6-oxo-, (Z)- (9CI)
YCA28979
DTXSID50622514
AKOS024049145
MB25655
MFCD16999751
CS-B1369
187151-99-1
PWQHSYDCGDVARU-UHFFFAOYSA-N
SY316629
1,4-Cyclohexadiene-1-carbonitrile, 3-(hydroxymethylene)-6-oxo-, (E)- (9CI)
5-FORMYL-2-HYDROXYBENZONITRILE
187152-05-2
73289-79-9
SCHEMBL1515823
5-formyl-2-hydroxybenzonitrile
Benzonitrile, 5-formyl-2-hydroxy- (9CI)
4-(Hydroxymethylene)-2-cyano-2,5-cyclohexadien-1-one

MDL Number

MFCD16999751

FAQ

What are the physical and chemical properties of 5-Formyl-2-hydroxybenzonitrile (CAS: 73289-79-9)?

5-Formyl-2-hydroxybenzonitrile is a white to off-white crystalline solid with a molecular weight of approximately 204.15 g/mol. It is slightly soluble in water but more soluble in polar organic solvents like ethanol and acetone. The compound is moderately reactive, showing electrophilic character, and can undergo nucleophilic substitution and condensation reactions.

How is 5-Formyl-2-hydroxybenzonitrile (CAS: 73289-79-9) typically synthesized?

5-Formyl-2-hydroxybenzonitrile is typically synthesized via a multistep process involving the reaction of 2-hydroxybenzonitrile with formic acid under mild conditions. This reaction involves esterification followed by hydrolysis to yield the desired product. Commonly used conditions include the presence of a catalyst like sulfuric acid and heating under reflux.

What industries use 5-Formyl-2-hydroxybenzonitrile (CAS: 73289-79-9)?

5-Formyl-2-hydroxybenzonitrile finds applications in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the production of functionalized polymers. Additionally, it has potential uses in the development of sensors and semiconductors due to its chemical reactivity and ability to form stable complexes.

What precautions should be taken when handling 5-Formyl-2-hydroxybenzonitrile (CAS: 73289-79-9)?

When handling 5-Formyl-2-hydroxybenzonitrile, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood due to its chemical reactivity. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local hazardous waste regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.