N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide

Basic Information

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CAS Number

73-31-4

Molecular Formula

C13H16N2O2

Molecular Weight

232.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

116.5-118 °C

Boiling Point

512.8°C at 760 mmHg

Density

1.1099 (rough estimate)

Solubility

Soluble in ethanol to at least 50mg/ml

Refractive Index

1.6450 (estimate)

Vapor Pressure

1.4X10-7 mm Hg at 25 °C (est)

SMILES

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COc1ccc2[nH]cc(CCNC(=O)C)c2c1

InChI

InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)

InChIKey

DRLFMBDRBRZALE-UHFFFAOYSA-N

LogP

1.8551

Topological Polar Surface Area

54.12 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

270

Safety Information

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Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H370 Causes damage to organs
Specific target organ toxicity, single exposure

Storage Conditions

2-8℃

Sensitiveness

Sensitive to light

Synonyms & References

English

N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
3-(N-ACETYL-2-AMINOETHYL)-5-METHOXYINDOLE
5-METHOXY-N-ACETYLTRYPTAMINE
ACETYL-5-METHOXYTRYPTAMINE
AKOS BB-4935
MELATONIN
MLT
N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE
N-(2-(5-methoxyindol-3-yl)ethyl)acetamide
N-ACETYL-5-METHOXYTRYPTAMINE
TIMTEC-BB SBB003265
Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-
Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-
Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)ethyl]
Melatonin(N-Acetyl-5-methoxytryptamine)
n-(2-(5-methoxy-1h-indol-3-yl)ethyl)-acetamid
n-(2-(5-methoxyindol-3-yl)ethyl)-acetamid
3-N-Acetyl-5-methoxyl tryptamine
MELATONIN F&amp
D VERSION FOR VETERINARY US
Melatonin (MLT)
MELATONIN(SH)
Melatonine
Circadin
Melatonin (AS)
Melovine
primex
[ "" ]
Melatol
Melatonex
N-[2-(5-methoxyindol-3-yl)ethyl]acetamide

MDL Number

MFCD00005655

Customs Code

2932999099

FAQ

What is N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide (CAS: 73-31-4)?

N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide, also known as melatonin (CAS: 73-31-4), is a naturally occurring hormone that regulates sleep-wake cycles. It is a derivative of tryptophan and has a molecular formula of C13H16N2O2. Melatonin is known for its antioxidant properties and plays a key role in circadian rhythm regulation. It is commonly used in supplements and pharmaceuticals for sleep disorders, and its chemical structure is well-documented in scientific research.

What are the main uses of N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide (CAS: 73-31-4)?

N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide (melatonin, CAS: 73-31-4) is primarily used in pharmaceuticals for treating sleep disorders such as insomnia. It is also applied in research for studying circadian rhythms and neuroprotection. In the food industry, it is used as a natural supplement in sleep aids and is found in some functional foods. Melatonin's role in antioxidant activity makes it valuable in health and wellness products.

Is N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide (CAS: 73-31-4) safe?

N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide (melatonin, CAS: 73-31-4) is generally considered safe when used appropriately. It is well-tolerated in most individuals and has low toxicity. However, long-term use or high doses may lead to side effects such as dizziness or nausea. Safety standards ensure its quality and purity in supplements and pharmaceuticals. Proper handling and storage are essential to maintain its efficacy and safety.

How should N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide (CAS: 73-31-4) be stored?

N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide (melatonin, CAS: 73-31-4) should be stored in a cool, dry place away from light. It is stable at room temperature but may degrade if exposed to high heat or moisture. To maintain its potency, it should be kept in a sealed container. Proper storage is crucial for preserving its chemical integrity and effectiveness in various applications.