(6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol

Basic Information

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CAS Number

722533-56-4

Molecular Formula

C30H38N2O2

Molecular Weight

458.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

SMILES

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CCNCCc1ccc(cc1)CN(CC)c2cc(ccc2[C@@H]3CCc4cc(ccc4C3)O)OC

InChI

InChI=1S/C30H38N2O2/c1-4-31-17-16-22-6-8-23(9-7-22)21-32(5-2)30-20-28(34-3)14-15-29(30)26-11-10-25-19-27(33)13-12-24(25)18-26/h6-9,12-15,19-20,26,31,33H,4-5,10-11,16-18,21H2,1-3H3/t26-/m1/s1

InChIKey

SIFNOOUKXBRGGB-AREMUKBSSA-N

LogP

5.851800000000007

Topological Polar Surface Area

44.730000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

578

Synonyms & References

English

Elacestrant
RAD1901
RAD-1901
FM6A2627A8
(6R)-6-[2-[ethyl-[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
Elacestrant [INN]
Elacestrant [USAN]
Elacestrant (USAN/INN)
Elacestrant [USAN:INN]
BDBM349630
US10208011, Compound RAD-
WHO 10247
DB06374
SB19607
D11671
Q27278069
(2R)-2-(2-(Ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-

MDL Number

MFCD30532693

FAQ

What are the physical and chemical properties of (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4)?

This compound is a crystalline solid with a molecular weight of approximately 464.58 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards strong acids and bases. It is prone to hydrolysis under basic conditions and can undergo nucleophilic substitution reactions.

How is (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4) typically synthesized?

This compound is synthesized via a multi-step process involving coupling reactions, aminations, and hydrolysis. Key steps include the synthesis of a benzyl ethylamine intermediate, followed by its coupling with a 4-methoxyaniline derivative. The reaction is catalyzed by palladium under mild conditions, with yields typically ranging from 60% to 75%.

What industries use (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4)?

This compound is primarily used in the pharmaceutical industry for the development of new drugs. It has potential applications in the polymer industry for the modification of polymer properties and in the semiconductor industry as a dopant material. Additionally, it can be used in sensor technology for detecting specific chemical species.

What precautions should be taken when handling (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4)?

When handling this compound, use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Ensure proper storage in a cool, dry place away from direct sunlight. In case of a spill, use appropriate absorbents and dispose of the waste in accordance with local regulations. Always consult the safety data sheet (SDS) for detailed safety information.

Related Compounds

1,3-Dibromo-2,4-dichloro-5-fluorobenzene structure

Compound Q&A

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2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

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Compound Q&A

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Compound Q&A

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NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

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Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

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1310404-58-0(2-(2,2,2-Trifluoroa...

Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

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Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...

(6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol | CAS No. 722533-56-4

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Synonyms & References

English

MDL Number

FAQ

What are the physical and chemical properties of (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4)?

How is (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4) typically synthesized?

What industries use (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4)?

What precautions should be taken when handling (6R)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol (CAS: 722533-56-4)?

Related Compounds

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What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

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