1-Ethyl-1H-imidazole-4-carboxylic acid | CAS No. 71925-07-0
1-Ethyl-1H-imidazole-4-carboxylic acid
Basic Information
CAS Number
71925-07-0
Molecular Formula
C6H8N2O2
Molecular Weight
140.14 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 1-ethyl-1H-imidazole-4-carboxylic acid
MDL Number
MFCD07376008
FAQ
What are the physical and chemical properties of 1-Ethyl-1H-imidazole-4-carboxylic acid (CAS: 71925-07-0)?
1-Ethyl-1H-imidazole-4-carboxylic acid is a crystalline solid with a molecular weight of approximately 150.22 g/mol. It has limited water solubility and is moderately soluble in organic solvents. This compound is known for its reactivity towards nucleophiles and its ability to form stable complexes with metal ions. It also exhibits basic properties due to the imidazole ring.
How is 1-Ethyl-1H-imidazole-4-carboxylic acid (CAS: 71925-07-0) typically synthesized?
1-Ethyl-1H-imidazole-4-carboxylic acid can be synthesized by the coupling of ethyl acetoacetate with 1H-imidazole in the presence of a base like sodium hydroxide. This reaction involves the nucleophilic substitution of the acetoacetate group by the amino group of imidazole. The yield can be improved by using a suitable solvent and ensuring proper mixing and temperature control.
What industries use 1-Ethyl-1H-imidazole-4-carboxylic acid (CAS: 71925-07-0)?
1-Ethyl-1H-imidazole-4-carboxylic acid finds applications in various industries. It is used in pharmaceuticals for the synthesis of certain drugs, in polymers as a monomer, and in sensors for detection of specific analytes. Additionally, it has potential uses in the semiconductor industry for the fabrication of electronic devices.
What precautions should be taken when handling 1-Ethyl-1H-imidazole-4-carboxylic acid (CAS: 71925-07-0)?
When handling 1-Ethyl-1H-imidazole-4-carboxylic acid, it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood during synthesis and handling to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the material should be disposed of according to local regulations. Refer to the safety data sheet (SDS) for detailed information on handling and disposal.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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