6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine | CAS No. 7190-80-9

6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine

Basic Information

CAS Number

7190-80-9

Molecular Formula

C11H7ClN4

Molecular Weight

230.66 g/mol

AD

Basic Physical Properties

Melting Point

201-203

C1=CC=C(C=C1)C2=NN=C3N2N=C(C=C3)Cl

InChI

InChI=1S/C11H7ClN4/c12-9-6-7-10-13-14-11(16(10)15-9)8-4-2-1-3-5-8/h1-7H

InChIKey

CTKDTIYRVIGDLE-UHFFFAOYSA-N

LogP

2.4447

Topological Polar Surface Area

43.08 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

244

Synonyms & References

English

  • FT-0714055
  • Probes2_000330
  • EN300-50852
  • HMS3437M07
  • 6-chloro-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazine
  • Q27145238
  • F1967-0573
  • AKOS004915205
  • 7190-80-9
  • 6-chloro-3-phenyl-[1,2,4]triazolo[4,3-a]pyridazine
  • CCG-127421
  • MFCD00277891
  • 6-Chloro-3-phenyl-1,2,4-triazolo[4 3-b]pyridazine
  • CTKDTIYRVIGDLE-UHFFFAOYSA-N
  • DTXSID40358719
  • AS-41848
  • CHEBI:75352
  • Z381425730
  • 1,2,4-Triazolo[4,3-b]pyridazine, 6-chloro-3-phenyl-
  • CBDivE_014044
  • SCHEMBL4784567
  • 6-CHLORO-3-PHENYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE
  • Probes1_000132
  • CHEMBL2447904
  • 6-CHLORO-3-PHENYL-1,2,4-TRIAZOLO[4,3-B]PYRIDAZINE
  • 1,2,4-triazolo[4,3-b]pyridazine, 6-chloro-3-phenyl-
  • 6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine
  • 6-CHLORO-3-PHENYL-1,2,4-TRIAZOLO[4 3-B]PYRIDAZINE
  • 6-Chlor-3-phenyl-1,2,4-triazolo<4,3-b>pyridazin
  • 6-Chloro-3-phenyl-s-triazolo<4,3-b>pyridazine

MDL Number

MFCD00277891

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine (CAS: 7190-80-9)?

6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine is a crystalline solid with a molecular weight of approximately 277.71 g/mol. It has a high solubility in organic solvents like DMF and poor solubility in water. The compound is less reactive compared to other chlorinated aromatic compounds, showing moderate reactivity in electrophilic aromatic substitution reactions.

How is 6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine (CAS: 7190-80-9) typically synthesized?

6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine can be synthesized through the condensation of 3-phenyl-1,2,4-triazol-5(4H)-one with chloroacetyl chloride, followed by amination. The synthesis typically involves the use of a base such as triethylamine and proceeds with good yield and selectivity.

What industries use 6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine (CAS: 7190-80-9)?

6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine is primarily used in the pharmaceutical industry for the development of new drugs. It also finds applications in organic electronics, particularly in the fabrication of organic semiconductors for thin-film transistors and organic light-emitting diodes.

What precautions should be taken when handling 6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine (CAS: 7190-80-9)?

When handling 6-Chloro-3-phenyl[1,2,4]triazolo[4,3-b]pyridazine, proper personal protective equipment (PPE) including gloves, goggles, and a lab coat should be worn. This compound should be used in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up immediately, and the area should be flushed with water. Always refer to the SDS for detailed safety information and follow all safety guidelines.

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