1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol

Basic Information

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CAS Number

718-64-9

Molecular Formula

C9H6F6O

Molecular Weight

244.13 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

160°C

Density

1.45 g/mL at 25 °C

Refractive Index

n20/D 1.415(lit.)

SMILES

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C1=CC=C(C=C1)C(C(F)(F)F)(C(F)(F)F)O

InChI

InChI=1S/C9H6F6O/c10-8(11,12)7(16,9(13,14)15)6-4-2-1-3-5-6/h1-5,16H

InChIKey

IZPIZCAYJQCTNG-UHFFFAOYSA-N

LogP

2.998800000000001

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

223

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

Benzyl alcohol,.alpha.-bis(trifluoromethyl)-
Benzenemethanol, .alpha.,.alpha.-bis(trifluoromethyl)-
FD10470
IZPIZCAYJQCTNG-UHFFFAOYSA-
FT-0604631
1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol
AS-48861
SCHEMBL542694
alpha,alpha-Bis(trifluoromethyl)benzyl alcohol
NSC 96337
A,A-Bis(trifluoromethyl)benzyl alcohol
718-64-9
Hexafluoro-2-phenyl isopropanol
DTXSID3061051
1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol
Hexafluoro-2-phenylpropan-2-ol
MFCD00040983
(Hexafluoro-2-hydroxyisopropyl)benzene
NSC96337
Benzenemethanol, alpha,alpha-bis(trifluoromethyl)-
SY049066
1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol, 99%
NS00042523
Hexafluoro-2-phenyl-2-propanol
H0724
hexafluoro-2-phenylisopropanol
2,2,2,2',2',2'-Hexafluorocumyl alcohol
NSC-96337
AKOS003619425
CHEMBL3955910
EINECS 211-943-4

MDL Number

MFCD00040983

Customs Code

2906299090

FAQ

What are the physical and chemical properties of 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol (CAS: 718-64-9)?

1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol has a crystalline form with a molecular weight of approximately 268.13 g/mol. It is moderately soluble in organic solvents like acetonitrile and dimethylformamide but is practically insoluble in water. Chemically, it is relatively stable but can react with strong bases to form hexafluoroisopropyl phenol salts.

How is 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol (CAS: 718-64-9) typically synthesized?

1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol is typically synthesized via hydrolysis of hexafluoroisopropyl phenyl carbonate using a protic acid as a catalyst. The process involves high yields and good selectivity, making it a suitable method for industrial production.

What industries use 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol (CAS: 718-64-9)?

1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol is used in the pharmaceutical industry for the synthesis of certain drugs, and in the polymer industry for the modification of polymers to improve their properties. It's also utilized in the sensor and semiconductor industries for specialized applications.

What precautions should be taken when handling 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol (CAS: 718-64-9)?

When handling 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol, it is important to wear protective gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, use appropriate PPE and follow the safety data sheet (SDS) guidelines for clean-up. Ensure proper storage in a cool, dry place, away from sources of heat and ignition.