1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol(CAS: 718-64-9)

1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol has a crystalline form with a molecular weight of approximately 268.13 g/mol. It is moderately soluble in organic solvents like acetonitrile and dimethylformamide but is practically insoluble in water. Chemically, it is relatively stable but can react with strong bases to form hexafluoroisopropyl phenol salts.

1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol is typically synthesized via hydrolysis of hexafluoroisopropyl phenyl carbonate using a protic acid as a catalyst. The process involves high yields and good selectivity, making it a suitable method for industrial production.

1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol is used in the pharmaceutical industry for the synthesis of certain drugs, and in the polymer industry for the modification of polymers to improve their properties. It's also utilized in the sensor and semiconductor industries for specialized applications.

When handling 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol, it is important to wear protective gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, use appropriate PPE and follow the safety data sheet (SDS) guidelines for clean-up. Ensure proper storage in a cool, dry place, away from sources of heat and ignition.