(5-Bromo-2-thienyl)acetonitrile

Basic Information

View in Editor

CAS Number

71637-37-1

Molecular Formula

C6H4BrNS

Molecular Weight

202.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=C(SC(=C1)Br)CC#N

InChI

InChI=1S/C6H4BrNS/c7-6-2-1-5(9-6)3-4-8/h1-2H,3H2

InChIKey

ZFTILCZVZSZDLI-UHFFFAOYSA-N

LogP

2.57668

Complexity

139

Synonyms & References

English

(5-BROMO-THIOPHEN-2-YL)-ACETONITRILE
DTXSID10355992
SCHEMBL1164376
CS-0043014
Z285575842
5-bromo-thiophene-2-acetonitrile
AKOS000165504
2-(5-bromothiophen-2-yl)acetonitrile
71637-37-1
ZFTILCZVZSZDLI-UHFFFAOYSA-N
FT-0769366
2-Thiopheneacetonitrile, 5-bromo-
5-Bromo-2-thiopheneacetonitrile
MFCD01859859
DS-4119
WCA63737
EN300-43001
2-(5-Bromothiophen-2-yl)acetonitrile
(5-Bromo-thiophen-2-yl)-acetonitrile
2-Thiopheneacetonitrile,5-bromo-
2-Thiopheneacetonitrile,5-bromo
5-Brom-2-thiophen-acetonitril
5-bromo-2-thiopheneacetonitrile

MDL Number

MFCD01859859

Customs Code

2934999090

FAQ

What are the physical and chemical properties of (5-Bromo-2-thienyl)acetonitrile (CAS: 71637-37-1)?

(5-Bromo-2-thienyl)acetonitrile is a crystalline solid with a molecular weight of approximately 229.04 g/mol. It is slightly soluble in water but more soluble in organic solvents like dichloromethane. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. Its physical properties include a melting point of around 60-62°C.

How is (5-Bromo-2-thienyl)acetonitrile (CAS: 71637-37-1) typically synthesized?

(5-Bromo-2-thienyl)acetonitrile can be synthesized via the bromination of 2-thienylacetonitrile followed by purification. Common methods include the use of N-bromosuccinimide (NBS) as a brominating agent in an organic solvent. The reaction is typically carried out at room temperature, with a yield of about 75-85%.

What industries use (5-Bromo-2-thienyl)acetonitrile (CAS: 71637-37-1)?

(5-Bromo-2-thienyl)acetonitrile is used in various industries, particularly in the pharmaceutical sector for the synthesis of intermediates in drug development. It is also used in the polymer industry for the production of certain plastics and resins, and in semiconductor manufacturing for photolithography processes.

What precautions should be taken when handling (5-Bromo-2-thienyl)acetonitrile (CAS: 71637-37-1)?

When handling (5-Bromo-2-thienyl)acetonitrile, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be handled in a fume hood due to its potential for inhalation hazards. Spills should be handled carefully, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information.