2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol | CAS No. 71636-38-9

2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol

Basic Information

CAS Number

71636-38-9

Molecular Formula

C19H24ClNO4

Molecular Weight

365.86 g/mol

AD

Basic Physical Properties

Melting Point

118-121 ºC

Density

1.191

COC1=CC=C(C=C1)C(CNCCC2=C(C(=C(C=C2)OC)OC)Cl)O

InChI

InChI=1S/C19H24ClNO4/c1-23-15-7-4-13(5-8-15)16(22)12-21-11-10-14-6-9-17(24-2)19(25-3)18(14)20/h4-9,16,21-22H,10-12H2,1-3H3

InChIKey

PQRXADLRQKVLHQ-UHFFFAOYSA-N

LogP

3.2315000000000027

Topological Polar Surface Area

59.95 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

365

Synonyms & References

English

  • A837268
  • AKOS015906836
  • 2-((2-Chloro-3,4-dimethoxyphenethyl)amino)-1-(4-methoxyphenyl)ethanol
  • PQRXADLRQKVLHQ-UHFFFAOYSA-N
  • DTXSID20992211
  • 2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethan-1-ol
  • W-104514
  • n-(2-hydroxy-2-(4-methoxyphenyl)ethyl)-2-(2-chloro-3,4-dimethoxyphenyl)ethylamine
  • AC-7641
  • EINECS 275-740-2
  • SCHEMBL8993202
  • N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-2-(2-chloro-3,4-dimethoxyphenyl)ethylamine
  • N-[2-HYDROXY-2(4-METHOXYPHENYL)ETHYL]-2-(2-CHLORO-3,4-DIMETHOXYPHENYL)ETHYLAMINE
  • FT-0651958
  • 2-[2-(2-chloro-3,4-dimethoxy-phenyl)ethylamino]-1-(4-methoxyphenyl)ethanol
  • 2-[2-(2-chloro-3,4-dimethoxyphenyl)ethylamino]-1-(4-methoxyphenyl)ethanol
  • 2-(2-chloro-3,4-dimethoxyphenethylamino)-1-(4-methoxyphenyl)ethanol
  • alpha-(((2-(2-Chloro-3,4-dimethoxyphenyl)ethyl)amino)methyl)-4-methoxybenzyl alcohol
  • DS-7059
  • 71636-38-9
  • NS00062895
  • alpha-[[[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-methoxy-benzenemethanol
  • N-[2-HYDROXY-2(4-METHOXYPHENYL)ETHYL]-2-(2-CHLORO-3,4-DIMETHOXYPHENYL)ETHYLAMINE(FENOLDOPAM INTERMEDIATE)
  • N-[2-hydroxy-2-(p-methoxyphenyl)ethyl]-2-(2-chloro-3,4-dimethoxyphenyl)ethylamine

MDL Number

MFCD07787564

Customs Code

2922509090

FAQ

What are the physical and chemical properties of 2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol (CAS: 71636-38-9)?

2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol is a crystalline compound with a molecular weight of approximately 455.86 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is mildly reactive under standard laboratory conditions and may undergo hydrolysis.

How is 2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol (CAS: 71636-38-9) typically synthesized?

2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol is typically synthesized via a multi-step process involving the coupling of a substituted phenol with an amino alcohol. This reaction is often catalyzed by a phase-transfer catalyst and proceeds with moderate yield under standard conditions.

What industries use 2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol (CAS: 71636-38-9)?

2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol finds applications in the pharmaceutical industry for drug synthesis and in the polymer industry for the development of novel materials. It is also used in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol (CAS: 71636-38-9)?

When handling 2-{[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol, it is essential to use personal protective equipment (PPE) such as gloves and safety goggles. Store it in a well-ventilated area and away from direct heat. In the event of a spill, ensure adequate fume hood use and follow appropriate spill cleanup procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.

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