(2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine | CAS No. 71620-89-8

(2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine

Basic Information

CAS Number

71620-89-8

Molecular Formula

C19H23NO3

Molecular Weight

313.4 g/mol

AD

Basic Physical Properties

CCOC1=CC=CC=C1OC(C2CNCCO2)C3=CC=CC=C3

InChI

InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19+/m1/s1

InChIKey

CBQGYUDMJHNJBX-MOPGFXCFSA-N

LogP

3.1938000000000004

Topological Polar Surface Area

39.72 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

333

Synonyms & References

English

  • Morpholine, 2-[(2-ethoxyphenoxy)phenylmethyl]-, (R*,R*)-
  • (R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine
  • CHEBI:135342
  • UNII-947S0YZ36I
  • (+/-)-(2R*)-2-((.ALPHA.R*)-.ALPHA.-(O-ETHOXYPHENOXY)BENZYL)MORPHOLINE
  • REBOXETINE [VANDF]
  • Reboxetine (INN)
  • Morpholine, 2-((R)-(2-ethoxyphenoxy)phenylmethyl)-, (2R)-rel-
  • CHEMBL383921
  • AKOS015966368
  • CS-0003444
  • Reboxe- tine
  • 41X
  • EN300-19659906
  • (2r)-2-[(R)-(2-Ethoxyphenoxy)(Phenyl)methyl]morpholine
  • REBOXETINE [MI]
  • BDBM388642
  • REBOXETINE [HSDB]
  • DB00234
  • 71620-89-8
  • Reboxetine [INN:BAN]
  • A837261
  • Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-
  • Reboxetine [INN]
  • 98769-81-4
  • (2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine
  • 947S0YZ36I
  • BCP12060
  • D08472
  • HSDB 7701
  • Norebox

MDL Number

MFCD11046031

FAQ

What are the physical and chemical properties of (2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8)?

(2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8) is a white crystalline solid with a molecular weight of approximately 329.36 g/mol. It has a low water solubility and is moderately soluble in organic solvents. The compound is relatively stable under normal conditions but can react with strong acids or bases. It is not typically flammable or explosive.

How is (2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8) typically synthesized?

(2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8) can be synthesized through a multistep reaction involving morpholine, 2-ethoxyphenol, and phenylmagnesium bromide. This reaction typically requires the use of a catalytic amount of a metal compound, such as lithium bromide, and proceeds under anhydrous conditions. The reaction yields a mixture that can be purified by recrystallization or column chromatography.

What industries use (2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8)?

(2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8) is primarily used in pharmaceuticals for its therapeutic applications. It may also find uses in the polymer industry for enhancing the performance of certain materials. Additionally, it could be used in sensors and semiconductors for specialized applications.

What precautions should be taken when handling (2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8)?

When handling (2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be managed carefully, and proper spill kits should be available. Always refer to the safety data sheet (SDS) for detailed safety instructions.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...