Compound Q&A

How is (2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8) typically synthesized?

Answer

(2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine
(2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine (CAS: 71620-89-8) can be synthesized through a multistep reaction involving morpholine, 2-ethoxyphenol, and phenylmagnesium bromide. This reaction typically requires the use of a catalytic amount of a metal compound, such as lithium bromide, and proceeds under anhydrous conditions. The reaction yields a mixture that can be purified by recrystallization or column chromatography.

About

CAS No 71620-89-8
English Name (2R)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine
Molecular Formula C19H23NO3
Molecular Weight 313.4 g/mol
SMILES CCOC1=CC=CC=C1OC(C2CNCCO2)C3=CC=CC=C3
InChIKey CBQGYUDMJHNJBX-MOPGFXCFSA-N
Last Updated: 2025-10-19 20:29

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