Ethyl 4-amino-2-pyrimidinecarboxylate

Basic Information

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CAS Number

71470-41-2

Molecular Formula

C7H9N3O2

Molecular Weight

167.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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CCOC(=O)C1=NC=CC(=N1)N

InChI

InChI=1S/C7H9N3O2/c1-2-12-7(11)6-9-4-3-5(8)10-6/h3-4H,2H2,1H3,(H2,8,9,10)

InChIKey

YHDZCFILDSOJRF-UHFFFAOYSA-N

LogP

0.23550000000000015

Topological Polar Surface Area

78.1 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

163

Synonyms & References

English

2-Pyrimidinecarboxylic acid, 4-amino-, ethyl ester
SCHEMBL10829516
4-amino-2-pyrimidinecarboxylic acid ethyl ester
ethyl 4-azanylpyrimidine-2-carboxylate
DS-11201
A837192
FT-0649815
4-Amino-pyrimidine-2-carboxylic acid ethyl ester
MFCD11973676
ethyl 4-aminopyrimidine-2-carboxylate
J-520971
YHDZCFILDSOJRF-UHFFFAOYSA-N
AM86025
71470-41-2
SB38423
CS-W006613
DTXSID80516750
SY106290
EN300-131555
2-Pyrimidinecarboxylicacid,4-amino-,ethyl ester
AKOS015854821
Ethyl 4-aminopyrimidine-2-carboxylate
2-Pyrimidinecarboxylicacid, 4-amino-, ethyl ester
AMMD00051
RP23008
FCH1152905
AX8159718
AB0026389
ST2412991
AB1010253
W8041

MDL Number

MFCD11973676

Customs Code

2933599090

FAQ

What are the physical and chemical properties of Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2)?

Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2) is a crystalline solid with a molecular weight of approximately 184.18 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and acetonitrile. The compound is generally stable, but it can undergo hydrolysis in basic conditions. It shows moderate reactivity towards nucleophiles.

How is Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2) typically synthesized?

Ethyl 4-amino-2-pyrimidinecarboxylate is typically synthesized via the reaction of ethyl 2-pyrimidinecarboxylate with an amine, such as ethylamine, in the presence of a base like potassium carbonate. The reaction proceeds via nucleophilic substitution, yielding the desired amino compound with high selectivity and yield.

What industries use Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2)?

Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for certain functional polymers, and in the sensor industry for the development of chemical sensors.

What precautions should be taken when handling Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2)?

When handling Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2), ensure to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place away from sources of heat and direct sunlight. Disposal should follow local regulations, and spills should be handled according to the Material Safety Data Sheet (MSDS). Always work under a fume hood and consult the SDS for detailed safety information.