Compound Q&A

How is Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2) typically synthesized?

Answer

Ethyl 4-amino-2-pyrimidinecarboxylate
Ethyl 4-amino-2-pyrimidinecarboxylate is typically synthesized via the reaction of ethyl 2-pyrimidinecarboxylate with an amine, such as ethylamine, in the presence of a base like potassium carbonate. The reaction proceeds via nucleophilic substitution, yielding the desired amino compound with high selectivity and yield.

About

CAS No 71470-41-2
English Name Ethyl 4-amino-2-pyrimidinecarboxylate
Molecular Formula C7H9N3O2
Molecular Weight 167.17 g/mol
SMILES CCOC(=O)C1=NC=CC(=N1)N
InChIKey YHDZCFILDSOJRF-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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