2-Methyl-4-piperidinone

Basic Information

View in Editor

CAS Number

71322-99-1

Molecular Formula

C6H11NO

Molecular Weight

113.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

CC1CC(=O)CCN1

InChI

InChI=1S/C6H11NO/c1-5-4-6(8)2-3-7-5/h5,7H,2-4H2,1H3

InChIKey

OFVHMZSKMQPCKB-UHFFFAOYSA-N

LogP

0.32739999999999997

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

101

Synonyms & References

English

SCHEMBL1360201
2-methylpiperidin-4-one
FT-0650621
4-Piperidinone, 2-methyl-
SB75341
A26725
SB11156
(2R)-2-methylpiperidin-4-one
AMY13581
W10112
DTXSID60406741
EN300-70832
(2S)-2-Methyl-4-piperidinone
OFVHMZSKMQPCKB-UHFFFAOYSA-N
AKOS005137897
71322-99-1
2-methyl-4-piperidone
2-METHYL-PIPERIDIN-4-ONE
CS-0080309
2-Methylpiperidin-4-one
2-Methyl-4-piperidinone
2-Methyl-4-piperidone
2-Methyl-piperidin-4-one
2-methyl-4-oxopiperidine
2-Methyl-piperidin-4-on
2-methyl-piperidine-4-one
4-Piperidinone,2-methyl

MDL Number

MFCD05861572

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-4-piperidinone (CAS: 71322-99-1)?

2-Methyl-4-piperidinone (CAS: 71322-99-1) is a colorless, crystalline solid with a piperidine-like odor. The molecular weight is approximately 126.21 g/mol. It has high solubility in water and organic solvents. It is moderately reactive, particularly in acid-catalyzed reactions. It is slightly basic and can react with acidic compounds to form adducts.

How is 2-Methyl-4-piperidinone (CAS: 71322-99-1) typically synthesized?

2-Methyl-4-piperidinone is typically synthesized via the ring-opening of 2-methyl-4-methyl-1,3-dioxolane-2-one using base, such as sodium hydroxide, under mild conditions. This method provides high yields and good selectivity. Other synthetic methods include the use of catalytic hydrogenation of methylpyrrole-2-one.

What industries use 2-Methyl-4-piperidinone (CAS: 71322-99-1)?

2-Methyl-4-piperidinone is widely used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry as a monomer, and in the sensor industry for gas sensing applications. It is also used in the semiconductor industry as a cleaning agent.

What precautions should be taken when handling 2-Methyl-4-piperidinone (CAS: 71322-99-1)?

When handling 2-Methyl-4-piperidinone, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a well-ventilated area away from heat and open flame. In case of spill, it should be cleaned up carefully under a fume hood, and appropriate safety data sheets (SDS) should be consulted for detailed handling procedures.