2-Methyl-4-piperidinone(CAS: 71322-99-1)

2-Methyl-4-piperidinone (CAS: 71322-99-1) is a colorless, crystalline solid with a piperidine-like odor. The molecular weight is approximately 126.21 g/mol. It has high solubility in water and organic solvents. It is moderately reactive, particularly in acid-catalyzed reactions. It is slightly basic and can react with acidic compounds to form adducts.

2-Methyl-4-piperidinone is typically synthesized via the ring-opening of 2-methyl-4-methyl-1,3-dioxolane-2-one using base, such as sodium hydroxide, under mild conditions. This method provides high yields and good selectivity. Other synthetic methods include the use of catalytic hydrogenation of methylpyrrole-2-one.

2-Methyl-4-piperidinone is widely used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry as a monomer, and in the sensor industry for gas sensing applications. It is also used in the semiconductor industry as a cleaning agent.

When handling 2-Methyl-4-piperidinone, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a well-ventilated area away from heat and open flame. In case of spill, it should be cleaned up carefully under a fume hood, and appropriate safety data sheets (SDS) should be consulted for detailed handling procedures.