Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate | CAS No. 71145-03-4
Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate
Basic Information
CAS Number
71145-03-4
Molecular Formula
C16H15F3N2O4
Molecular Weight
356.3 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
166 °C
Density
1.3548 (estimate)
Water Solubility
Soluble in DMSO at 20mg/ml. Also soluble in methanol or ethanol at 60mg/ml. Insoluble in water
Solubility
DMSO: 184 mg/mL
Safety Information
View Safety InformationStability
Stable. Incompatible with strong oxidizing agents.
Synonyms & References
English
- Bio1_000030
- BAY-K-8644
- BAYK 8644; BAYK8644; BAYK-8644;Bay K8644;Bay K 8644
- NCGC00025209-03
- AM20080536
- s7924
- BCP15942
- SMR000058424
- (+/-)-Bay K8644, calcium channel agonist
- MLS002153190
- HMS3886L19
- BSPBio_001578
- Z1213715450
- MFCD00036697
- HMS2231A11
- EX-A4933
- GTPL2511
- (?)-Bay K 8644
- NCGC00260871-01
- A837092
- NCGC00015124-04
- Opera_ID_789
- HMS3268C13
- Methyl 2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate
- HMS3370M19
- methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
- EX-A3340
- MLS000028858
- (+/-)-BAY-K-8644
- CHEMBL1322959
- BDBM50035800
MDL Number
MFCD00036697
FAQ
What are the physical and chemical properties of Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate (CAS: 71145-03-4)?
Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate has a crystalline form with a molecular weight of approximately 429.3 g/mol. It is sparingly soluble in water but soluble in organic solvents like methanol and ethanol. The compound is chemically stable but reactive towards reducing agents. It has a characteristic melting point around 160-165°C.
How is Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate (CAS: 71145-03-4) typically synthesized?
Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate is synthesized via a multi-step process involving the reaction of 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]pyridine with acetic anhydride. The reaction is catalyzed by an acid, typically sulfuric acid, under reflux conditions. The yield is around 85%, and the product is purified by recrystallization.
What industries use Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate (CAS: 71145-03-4)?
Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate is used in the pharmaceutical industry for the synthesis of various drug molecules. It is also utilized in the chemical industry for the development of new materials and in the production of sensors and semiconductors due to its unique chemical structure.
What precautions should be taken when handling Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate (CAS: 71145-03-4)?
When handling Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate, it is essential to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a fume hood to minimize exposure. In case of a spill, it should be contained and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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