Histidine | CAS No. 71-00-1

Histidine

Basic Information

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CAS Number

71-00-1

Molecular Formula

C6H9N3O2

Molecular Weight

155.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

282 °C (dec.)

Boiling Point

278.95°C (rough estimate)

Density

1.3092 (rough estimate)

Water Solubility

41.6 g/L (25 ºC)

Flash Point

282oC

Solubility

H2O: 50 mg/mL

Refractive Index

13 ° (C=11, 6mol/L HCl)

Specific Rotation

12.4 º (c=11,6N HCl)

SMILES

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N[C@@H](Cc1c[nH]cn1)C(=O)O

InChI

InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChIKey

HNDVDQJCIGZPNO-YFKPBYRVSA-N

LogP

-0.6359000000000001

pKa

1.8(at 25℃)

Topological Polar Surface Area

92.00000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

151

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

photosensitive

Synonyms & References

English

L-Histidine
L-Histidine,free base
(S)-2-Amino-3-(4-imidazolyl)propionic acid~H-His-OH
L-Histidine Base
H-His-OH
L-Hisidine
CultureSure L-Histidine, Animal-derived-free
Histidine
HISTIDINE, L-(P)
HISTIDINE, L-(RG)
L-[+]-Histidine
L-HISTIDINE AJI 92
d,l-histidine
FEMA 3694
Histidin
H-L-HIS-OH
L-HIS
L-Histdine
NSC 137773
L-2-Amino-3-(4-imidazolyl)propionic acid
glyoxaline-5-alanine
Anti-rheuma
L-(-)-Histidine
Istidina
S-Histidine
(L)-Histidine
Histidine (VAN)
histidina
(S)-4-(2-Amino-2-carboxyethyl)imidazole
Histidinum
(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid

MDL Number

MFCD00064315

Customs Code

2933290090

FAQ

What is Histidine (CAS: 71-00-1)?

Histidine is an essential amino acid with the chemical formula C6H9N3O2. It plays a critical role in protein synthesis and is involved in various physiological functions, including pH regulation and neurotransmitter production. Histidine is also a precursor for histamine, a compound important in immune responses and digestion. It is commonly found in foods like meat, fish, and dairy and is used in pharmaceuticals and nutritional supplements. Its unique properties make it valuable in both biological and industrial contexts.

What are the main uses of Histidine (CAS: 71-00-1)?

Histidine has diverse applications. It is used in pharmaceuticals as a buffer and in drug formulations to stabilize active ingredients. In the food industry, it serves as a flavor enhancer and nutrient supplement. It is also essential in research for studying protein structure and function. Additionally, histidine is used in the production of histamine, which is important in medical treatments and food preservation. Its role in human health makes it a key component in dietary and therapeutic products.

Is Histidine (CAS: 71-00-1) safe?

Histidine is generally safe when consumed in appropriate amounts through food or supplements. It is considered non-toxic and well-tolerated by the human body. However, high doses may cause side effects such as gastrointestinal discomfort. In industrial settings, proper handling and protective measures are recommended to avoid skin or respiratory irritation. Safety standards ensure its use in food, medicine, and research is controlled and appropriate.

How should Histidine (CAS: 71-00-1) be stored?

Histidine should be stored in a cool, dry, and dark place to maintain its stability and prevent degradation. It is best kept in airtight containers to avoid moisture and contamination. The ideal storage temperature is below 25°C, with low humidity levels. Exposure to light and air should be minimized. Proper storage is essential for preserving the compound's quality and effectiveness in pharmaceutical, food, and research applications.