Is Histidine (CAS: 71-00-1) safe?

Histidine is generally safe when consumed in appropriate amounts through food or supplements. It is considered non-toxic and well-tolerated by the human body. However, high doses may cause side effects such as gastrointestinal discomfort. In industrial settings, proper handling and protective measures are recommended to avoid skin or respiratory irritation. Safety standards ensure its use in food, medicine, and research is controlled and appropriate.