1H-Indol-7-yl(phenyl)methanone

Basic Information

View in Editor

CAS Number

70803-96-2

Molecular Formula

C15H11NO

Molecular Weight

221.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

View in Editor

C1=CC=C(C=C1)C(=O)C2=CC=CC3=C2NC=C3

InChI

InChI=1S/C15H11NO/c17-15(12-5-2-1-3-6-12)13-8-4-7-11-9-10-16-14(11)13/h1-10,16H

InChIKey

FIAMTEUKWUNTSP-UHFFFAOYSA-N

LogP

3.398900000000001

Topological Polar Surface Area

32.86 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

283

Synonyms & References

English

SCHEMBL9142579
70803-96-2
7-BENZOYLINDOLE
BCP34161
CHEMBL3249491
CS-0362759
(1H-Indol-7-yl)(phenyl)methanone
FIAMTEUKWUNTSP-UHFFFAOYSA-N
Bromfenac Impurity 20
7-benzoyl-1H-indole
F18013
Methanone, 1H-indol-7-ylphenyl-
AKOS015965002
DTXSID80446861
1H-indol-7-yl(phenyl)methanone
7-benzoylindole

MDL Number

MFCD09033129

FAQ

What are the physical and chemical properties of 1H-Indol-7-yl(phenyl)methanone (CAS: 70803-96-2)?

1H-Indol-7-yl(phenyl)methanone is a crystalline compound with a molecular weight of approximately 252.27 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and ethanol. Chemically, it exhibits moderate reactivity, particularly towards nucleophilic substitution and oxidation reactions.

How is 1H-Indol-7-yl(phenyl)methanone (CAS: 70803-96-2) typically synthesized?

1H-Indol-7-yl(phenyl)methanone is typically synthesized via the condensation of indole with phenylmethanol in the presence of a Lewis acid catalyst such as aluminum trichloride or zinc bromide. The reaction is carried out under reflux conditions, and the yield can be up to 85%.

What industries use 1H-Indol-7-yl(phenyl)methanone (CAS: 70803-96-2)?

1H-Indol-7-yl(phenyl)methanone is used in the pharmaceutical industry for the development of certain drugs, and it has potential applications in the polymer industry for creating advanced materials. It is also explored in the field of sensors and semiconductors for its unique electronic properties.

What precautions should be taken when handling 1H-Indol-7-yl(phenyl)methanone (CAS: 70803-96-2)?

When handling 1H-Indol-7-yl(phenyl)methanone, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be properly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.