Human serum albumin | CAS No. 70024-90-7

Human serum albumin

Basic Information

CAS Number

70024-90-7

Molecular Formula

C19H30ClN5O6

Molecular Weight

459.92 g/mol

EINECS

274-272-6

AD

Basic Physical Properties

Water Solubility

Soluble in water.

Solubility

H2O: 50 mg/mL, hazy, light-yellow

Cl.O1CCCC1C(N1CCN(C2N=C(C3C=C(C(=CC=3N=2)OC)OC)N)CC1)=O.O.O

InChI

1S/C19H25N5O4.ClH.2H2O/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;;;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H;2*1H2

InChIKey

NZMOFYDMGFQZLS-UHFFFAOYSA-N

LogP

-0.17080000000000056

Topological Polar Surface Area

166.04 Ų

Hydrogen Bond Donor/Acceptor

6 / 11

Complexity

544

Safety Information

View Safety Information

Storage Conditions

2-8°C

Stability

Stable. Incompatible with strong oxidizing agents.

Synonyms & References

English

  • ALBUMIN, HUMAN
  • RSA
  • RAT ALBUMIN
  • rHSA
  • ALBUMIN FROM HUMAN SERUM
  • ALBUMIN, HUMAN PROTEASE FREE
  • ALBUMIN, HUMAN LOW ENDOTOXIN
  • ALBUMIN, HUMAN, 1X CRYSTALLIZED
  • ALBUMIN, HUMAN A
  • HAS
  • AlbuMin froM HuMan, fraction V
  • Cellastim™
  • Albagen™
  • Recombinant human albumin
  • Human Serum Albumin
  • Albumin human
  • Terazosin hydrochloride dihydrate
  • Magnurol
  • Terazosin HCl
  • Flotrin
  • Heitrin
  • Hytrine
  • Terazosin HCl dihydrate
  • Hytrin
  • Urodie
  • Terazosin (hydrochloride dihydrate)
  • Zayasel
  • Terazosin HCl hydrate
  • Terazosin monohydrochloride dihydrate
  • (4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone hydrochloride dihydrate
  • Adecur

MDL Number

MFCD00081418

EC Number

274-272-6

Customs Code

35029000

FAQ

What are the physical and chemical properties of Human serum albumin (CAS: 70024-90-7)?

Human serum albumin (HSA) is a protein with a molecular weight of approximately 66,460 Da. It has a high solubility in water, making it suitable for intravenous administration. HSA is generally stable in neutral and slightly acidic pH conditions but can denature under extreme conditions. It is not highly reactive but can undergo proteolysis under proteolytic enzymes.

How is Human serum albumin (CAS: 70024-90-7) typically synthesized?

Human serum albumin (HSA) can be obtained either from human plasma or through recombinant DNA technology. Plasma-derived HSA is collected from human donors, while recombinant HSA is produced by expressing the albumin gene in a suitable host, such as yeast or mammalian cells, offering a more controlled and scalable production method.

What industries use Human serum albumin (CAS: 70024-90-7)?

Human serum albumin (HSA) is primarily used in the pharmaceutical industry for its role as a plasma volume expander and in the treatment of certain blood disorders. It is also utilized in the medical field for dialysis solutions, and in research for protein studies and as a stabilizer in biological products. Additionally, it is used in the food industry for its emulsifying properties.

What precautions should be taken when handling Human serum albumin (CAS: 70024-90-7)?

When handling Human serum albumin (HSA), it is essential to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and goggles. Store HSA in a cool, dry place away from direct sunlight and ensure proper labeling. In case of a spill, neutralize the area with a suitable cleaning agent and dispose of waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.

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