Human serum albumin(CAS: 70024-90-7)

Human serum albumin (HSA) is a protein with a molecular weight of approximately 66,460 Da. It has a high solubility in water, making it suitable for intravenous administration. HSA is generally stable in neutral and slightly acidic pH conditions but can denature under extreme conditions. It is not highly reactive but can undergo proteolysis under proteolytic enzymes.

Human serum albumin (HSA) can be obtained either from human plasma or through recombinant DNA technology. Plasma-derived HSA is collected from human donors, while recombinant HSA is produced by expressing the albumin gene in a suitable host, such as yeast or mammalian cells, offering a more controlled and scalable production method.

Human serum albumin (HSA) is primarily used in the pharmaceutical industry for its role as a plasma volume expander and in the treatment of certain blood disorders. It is also utilized in the medical field for dialysis solutions, and in research for protein studies and as a stabilizer in biological products. Additionally, it is used in the food industry for its emulsifying properties.

When handling Human serum albumin (HSA), it is essential to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and goggles. Store HSA in a cool, dry place away from direct sunlight and ensure proper labeling. In case of a spill, neutralize the area with a suitable cleaning agent and dispose of waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.