3-Iodotyrosine

Basic Information

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CAS Number

70-78-0

Molecular Formula

C9H10INO3

Molecular Weight

307.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

210 °C (dec.)

Boiling Point

391ºC at 760 mmHg

Density

1.7280 (estimate)

Flash Point

190.3ºC

Solubility

dilute aqueous acid: soluble

Refractive Index

1.688

SMILES

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C1=CC(=C(C=C1CC(C(=O)O)N)I)O

InChI

InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1

InChIKey

UQTZMGFTRHFAAM-ZETCQYMHSA-N

LogP

0.9512

Topological Polar Surface Area

83.55 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

212

Safety Information

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Sensitiveness

Light Sensitive

Synonyms & References

English

Monoiodotyrosine
SDCCGSBI-0050652.P002
I-7700
3-Iodo-L-tyrosine (I-Tyr)
(2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid
3-Monoiodo-L-tyrosine
NSC 210787
4-Hydroxy-3-iodophenylalanine
MLS000069664
H-3-Iodo-Tyr-OH
C02515
3-Iodo-4-hydroxyphenylalanine
L-Tyrosine, 3-iodo-
bmse000337
cid_439744
HMS3262G07
SR-01000075606-1
NSC-210787
FRQ98U4U27
3-IODOTYROSINE
Tyrosine, 3-iodo-, L-
DB01758
EINECS 200-744-8
3-IODOTYROSINE [MI]
LP00673
(2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoate
4-Hydroxy-3-iodophenylalanine #
CHEMBL479789
I0075
SMR000059143
Tyrosine, 3-iodo-, DL-

MDL Number

MFCD00063938

Customs Code

2922509090

FAQ

What are the physical and chemical properties of 3-Iodotyrosine (CAS: 70-78-0)?

3-Iodotyrosine (CAS: 70-78-0) is a crystalline solid with a molecular weight of approximately 243.79 g/mol. It is slightly soluble in water and ethanol. Chemically, it shows reactivity similar to other aromatic compounds, undergoing typical reactions such as electrophilic substitution. Its iodine group makes it susceptible to deiodination under certain conditions.

How is 3-Iodotyrosine (CAS: 70-78-0) typically synthesized?

3-Iodotyrosine is typically synthesized by the iodination of tyrosine. This process involves treating tyrosine with iodine in the presence of a base like sodium hydroxide. The reaction is often performed in an aqueous medium, and the selectivity for the iodination can be controlled by adjusting the reaction conditions. The yield and purity of the product can be improved using appropriate purification techniques.

What industries use 3-Iodotyrosine (CAS: 70-78-0)?

3-Iodotyrosine (CAS: 70-78-0) finds applications in the pharmaceutical industry due to its structural similarity to tyrosine, which is a key amino acid in drug development. It is also used in the production of certain sensors and in the synthesis of semiconductors, particularly in the preparation of materials for photoelectronic devices.

What precautions should be taken when handling 3-Iodotyrosine (CAS: 70-78-0)?

When handling 3-Iodotyrosine (CAS: 70-78-0), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be contained and cleaned up using appropriate methods. Always refer to the Safety Data Sheet (SDS) for detailed instructions on handling and storage. Storage should be in a cool, dry place, away from direct sunlight and flammable materials.