2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol

Basic Information

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CAS Number

6976-37-0

Molecular Formula

C8H19NO5

Molecular Weight

209.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

103-104 ºC

Boiling Point

466.2 ℃ at 760 mmHg

Density

1.3460

Flash Point

288℃

Solubility

H2O: 1 M at 20 °C, clear, colorless

SMILES

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OCCN(C(CO)(CO)CO)CCO

InChI

InChI=1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2

InChIKey

OWMVSZAMULFTJU-UHFFFAOYSA-N

LogP

-3.011299999999999

pKa

6.5(at 25℃)

Topological Polar Surface Area

104.39000000000001 Å²

Hydrogen Bond Donor/Acceptor

5 / 6

Complexity

125

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

Bis(2-Hydroxyethyl)aminotris(hydroxymethyl)methane
Bis(2-hydroxyethyl)-imino-tris-(hydroxymethyl)-methane biological buffer
bis-tris cell culture tested
Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane~Bis-TRIS
bis-tris free base
Bis Tris Bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane
Bis Tris, Molecular Biology Grade Bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane, Molecular Biology Grade
BIS-Tris, ULTROL Grade
2,2-Bis(hydroxymethyl)-2,2?2-nitrilotriethanol
BIS-TRIS
BIS(2-HYDROXYETHYL)IMINOTRIS(HYDROXYMETHYL)METHANE
BIS(2-HYDROXYETHYL)IMINO-TRIS(HYDROXYMETHYL)PROPANE
BIS(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE
BIS(HYDROXYETHYL)IMINO-TRIS-(HYDROXYMETHYL)-METHANE
''BIS-TRIS''
BIS-TRIS BUFFER
2,2-BIS(HYDROXYMETHYL)-2,2',2''-NITRILOETHANOL
Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research]
2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol
2,2-Bis(Hydroxymethyl)-2,2,2-Nitrilotriethanol
2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol
Bis(2-hydroxyethyl)iminotris(hydroxymethyl)methane BIS-TRIS
Bistris
1,3-Propanediol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Q1XC3631CP
2-(Bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)propane-1,3-d
Bis(2-hydroxyethyl)iminotris(hydroxymethyl)methane
Bis-Tris

MDL Number

MFCD00002853

Customs Code

29221980

FAQ

What is 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol (CAS: 6976-37-0)?

2-[Bis(2-hydroryethyl)amino]-2-(hydroxymethyl)-1,3-propanediol (CAS: 6976-37-0) is a multifunctional organic compound with three hydroxyl groups and two amino groups. It is a colorless liquid with high water solubility, neutral pH, and hydrophilic properties. This compound is commonly used as a chelating agent and stabilizer in various industrial and pharmaceutical applications.

What are the main uses of 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol (CAS: 6976-37-0)?

The compound finds applications in pharmaceuticals as a buffer and excipient, in industrial processes as a chemical intermediate, in food additives for pH regulation, and in research for stabilizing sensitive compounds. Its unique structure enables it to interact with metals and enhance product stability in diverse fields.

Is 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol (CAS: 6976-37-0) safe?

When handled properly, 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol (CAS: 6976-37-0) is considered safe. It has low toxicity and is generally recognized as safe (GRAS) for food use. However, protective measures like gloves and ventilation are recommended to avoid skin or eye contact. Safety data sheets (SDS) should be consulted for detailed guidelines.

How should 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol (CAS: 6976-37-0) be stored?

Store the compound in a sealed, airtight container at 2-8°C in a cool, dry, and dark location. Avoid exposure to moisture, heat, and direct light to maintain stability. Use inert materials for containment and ensure proper labeling to prevent contamination or accidental use.